An International, Multicenter Evaluation of Comprehensive Medication Management by Pharmacists in ICU Recovery Centers.

Autor: Stollings JL; Department of Pharmaceutical Services, Vanderbilt University Medical Center, Nashville, TN, USA.; Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Nashville, TN, USA., Poyant JO; Department of Pharmacy, Tufts Medical Center, Boston, MA, USA., Groth CM; Department of Pharmacy, University of Rochester Medical Center, Rochester, NY, USA., Rappaport SH; Department of Pharmacy, University of Rochester Medical Center, Rochester, NY, USA., Kruer RM; Department of Pharmacy, Indiana University Health, Adult Academic Health Center, Indianapolis, IN, USA., Miller E; Department of Pharmacy, Indiana University Health, Adult Academic Health Center, Indianapolis, IN, USA., Whitten JA; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA., Mcintire AM; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA., McDaniel CM; Department of Pharmacy, Thomas Jefferson University Hospital, Philadelphia, PA, USA., Betthauser KD; Department of Pharmacy Services, Barnes-Jewish Hospital, St. Louis, MO, USA., Mohammad RA; Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA., Kenes MT; Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA., Korona RB; Department of Pharmacy, Atrium Health Wake Forest Baptist, Winston-Salem, NC, USA., Barber AE; Department of Pharmacy, Atrium Health Wake Forest Baptist, Winston-Salem, NC, USA., MacTavish P; Pharmacy Department, Glasgow Royal Infirmary, Glasgow, Scotland., Dixit D; Ernest Mario School of Pharmacy, Rutgers University, New Brunswick, NJ, USA., Yeung SYA; Department of Pharmacy Services, University of Maryland Medical Center, Baltimore, MD, USA.
Jazyk: angličtina
Zdroj: Journal of intensive care medicine [J Intensive Care Med] 2023 Oct; Vol. 38 (10), pp. 957-965. Date of Electronic Publication: 2023 May 17.
DOI: 10.1177/08850666231176194
Abstrakt: Background: Post-intensive care syndrome (PICS) is defined as a new or worsening impairment in physical, cognitive, or mental health following critical illness. Intensive care unit recovery centers (ICU-RC) are one means to treat patients who have PICS. The purpose of this study is to describe the role of pharmacists in ICU-RCs.
Research Question: What is the number and type of medication interventions made by a pharmacist at an ICU-RC at 12 different centers?
Study Design and Methods: This prospective, observational study was conducted in 12 intensive care units (ICUs)/ICU-RCs between September 2019 and July 2021. A full medication review was conducted by a pharmacist on patients seen at the ICU-RC.
Results: 507 patients were referred to the ICU-RC. Of these patients, 474 attended the ICU-RC and 472 had a full medication review performed by a pharmacist. Baseline demographic and hospital course data were obtained from the electronic health record and at the ICU-RC appointment. Pharmacy interventions were made in 397 (84%) patients. The median number of pharmacy interventions per patient was 2 (interquartile range [IQR] = 1,3). Medications were stopped and started in 124 (26%) and 91 (19%) patients, respectively. The number of patients that had a dose decreased and a dose increased was 51 (11%) and 43 (9%), respectively. There was no difference in the median total number of medications that the patient was prescribed at the start and end of the patient visit (10, IQR = 5, 15). Adverse drug event (ADE) preventive measures were implemented in 115 (24%) patients. ADE events were identified in 69 (15%) patients. Medication interactions were identified in 30 (6%) patients.
Interpretation: A pharmacist plays an integral role in an ICU-RC resulting in the identification, prevention, and treatment of medication-related problems. This paper should serve as a call to action on the importance of the inclusion of a pharmacist in ICU-RC clinics.
Databáze: MEDLINE