NCTC3000: a century of bacterial strain collecting leads to a rich genomic data resource.

Autor: Dicks J; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Fazal MA; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Oliver K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK., Grayson NE; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK.; Present address: Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK, OX3 9DU, UK., Turnbull JD; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Bane E; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Burnett E; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Deheer-Graham A; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Holroyd N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK., Kaushal D; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Keane J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK., Langridge G; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK.; Present address: Quadram Institute Bioscience, Norwich Research Park, Norwich, NR4 7UQ, UK., Lomax J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK., McGregor H; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Picton S; Pacific Biosciences, 1305 O'Brien Drive, Menlo Park, CA, USA., Quail M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK., Singh D; Pacific Biosciences, 1305 O'Brien Drive, Menlo Park, CA, USA., Tracey A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK., Korlach J; Pacific Biosciences, 1305 O'Brien Drive, Menlo Park, CA, USA., Russell JE; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Alexander S; Culture Collections, UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ, UK., Parkhill J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK.; Present address: Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK.
Jazyk: angličtina
Zdroj: Microbial genomics [Microb Genom] 2023 May; Vol. 9 (5).
DOI: 10.1099/mgen.0.000976
Abstrakt: The National Collection of Type Cultures (NCTC) was founded on 1 January 1920 in order to fulfil a recognized need for a centralized repository for bacterial and fungal strains within the UK. It is among the longest-established collections of its kind anywhere in the world and today holds approximately 6000 type and reference bacterial strains - many of medical, scientific and veterinary importance - available to academic, health, food and veterinary institutions worldwide. Recently, a collaboration between NCTC, Pacific Biosciences and the Wellcome Sanger Institute established the NCTC3000 project to long-read sequence and assemble the genomes of up to 3000 NCTC strains. Here, at the beginning of the collection's second century, we introduce the resulting NCTC3000 sequence read datasets, genome assemblies and annotations as a unique, historically and scientifically relevant resource for the benefit of the international bacterial research community.
Databáze: MEDLINE