PANCREATIC CANCER MORTALITY TRENDS AND CORRELATION WITH HUMAN DEVELOPMENT INDEX (HDI) IN BRAZIL OVER 40 YEARS.

Autor:	Silva DRME; Universidade de São Paulo, Faculdade de Saúde Pública, Programa de Pós-Graduação em Epidemiologia, São Paulo, SP, Brasil.; A.C.Camargo Câncer Center, Registro Hospitalar de Câncer, São Paulo, SP, Brasil., Oliveira MM; Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Departamento de Saúde Coletiva, Goiânia, GO, Brasil., Fernandes GA; A.C.Camargo Câncer Center, Grupo de Epidemiologia e Estatística do Câncer, São Paulo, SP, Brasil., Curado MP; Universidade de São Paulo, Faculdade de Saúde Pública, Programa de Pós-Graduação em Epidemiologia, São Paulo, SP, Brasil.; A.C.Camargo Câncer Center, Registro Hospitalar de Câncer, São Paulo, SP, Brasil.; A.C.Camargo Câncer Center, Grupo de Epidemiologia e Estatística do Câncer, São Paulo, SP, Brasil.
Jazyk:	angličtina
Zdroj:	Arquivos de gastroenterologia [Arq Gastroenterol] 2023 Jan-Mar; Vol. 60 (1), pp. 30-38.
DOI:	10.1590/S0004-2803.202301000-05
Abstrakt:	Background: Pancreatic cancer mortality is greater in countries with a high Human Development Index (HDI). This study analyzed pancreatic cancer mortality rates trends, and their correlation with HDI in Brazil over 40 years. Methods: Data on pancreatic cancer mortality in Brazil between 1979 and 2019 were obtained from the Mortality Information System (SIM). Age-standardized mortality rates (ASMR) and Annual Average Percent Change (AAPC) were calculated. Pearson's correlation test was applied to compare mortality rates and HDI for three periods: 1986-1995 was correlated with HDI of 1991, 1996-2005 with HDI of 2000, and 2006-2015 with HDI of 2010; and to the correlation of AAPC versus the percentage change in HDI from 1991 to 2010. Results: A total of 209,425 deaths from pancreatic cancer were reported in Brazil, with an annual increase of 1.5% in men and 1.9% in women. There was an upward trend for mortality in most Brazilian states, with the highest trends observed in the North and Northeast states. A positive correlation between pancreatic mortality and HDI was observed over the three decades (r>0.80, P<0.05) and also between AAPC and HDI improvement by sex (r=0.75 for men and r=0.78 for women, P<0.05). Conclusion: There was an upward trend in pancreatic cancer mortality in Brazil for both sexes, but rates among women were higher. Mortality trends were higher in states with a higher percentage improvement in HDI, such as the North and Northeast states.
Databáze:	MEDLINE
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