Investigation into the potential of using UV-treated sporulated oocysts of Eimeria tenella as a local solution to immunization of chickens against caecal coccidiosis.

Autor: Djemai S; Laboratoire de Recherche de Pathologie Animale Développement des Elevages et Surveillance de la Chaine Alimentaire des Denrées Animales ou d'origine Animale (PADESCA), Institute of Veterinary Sciences, University of Constantine, Constantine, Algeria., Mekroud A; Laboratoire de Recherche de Pathologie Animale Développement des Elevages et Surveillance de la Chaine Alimentaire des Denrées Animales ou d'origine Animale (PADESCA), Institute of Veterinary Sciences, University of Constantine, Constantine, Algeria., Hide G; Biomedical Research Centre, School of Science, Engineering and Environment, University of Salford, Salford, UK., Khelifi D; Laboratoire de Génétique Biochimie Biotechnolgies Végétales (BBGV), University of Constantine, Constantine, Algeria., Bellil I; Laboratoire de Génétique Biochimie Biotechnolgies Végétales (BBGV), University of Constantine, Constantine, Algeria.
Jazyk: angličtina
Zdroj: Journal of parasitic diseases : official organ of the Indian Society for Parasitology [J Parasit Dis] 2023 Jun; Vol. 47 (2), pp. 238-245. Date of Electronic Publication: 2023 Jan 07.
DOI: 10.1007/s12639-022-01562-7
Abstrakt: In this study, we aim to evaluate the immune response of chickens to UV-treated sporulated oocysts as a means of protection against caecal coccidiosis caused by field strains of Eimeria tenella . Two groups of chicks were immunized using prepared UV-treated oocysts of E. tenella and challenged at day 20 post hatching. The first group was immunized only once at day 1 post hatching, the second group was immunized twice (day 1 and day 8 post hatching). Two non-immunized control groups were used: the first group was challenged with E. tenella , while the second group remained uninfected. The effectiveness of immunization on production and animal health was evaluated by the following criteria: body weight, feed conversion ratio, blood in faeces, mortality, lesion scores and oocyst output. The two immunized groups showed a significantly better performance in body weight, weight gain and lesion scores than the non-immunized group. However, all three groups performed significantly worse than the unchallenged group. The mortality of the non-immunized infected group was high (70%) while mortality in both immunized and unchallenged groups of chickens was significantly lower (range 2.2 to 4.4%) than the infected group ( p  < 0.05). The production of oocysts in faeces, post-infection, was significantly higher in the non-immunized group compared to the immunized group ( p  < 0.05) and both were significantly higher than the uninfected group ( p  < 0.05). In conclusion, immunization by prepared UV-irradiated oocysts is effective in stimulating at least a partial protective immunity in immunized chickens against caecal coccidiosis.
Competing Interests: Conflicts of interestThe authors declare that they have no conflict of interest.
(© Indian Society for Parasitology 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE
Externí odkaz: