Cardiac Tamponade as a Complication of Microscopic Polyangiitis: A Case Associated With a COVID-19 mRNA Vaccine.

Autor: Avalos C; Rheumatology, State University of New York Downstate Medical Center, New York, USA., Ahmadzadeh Y; Internal Medicine, Roger Williams Medical Center, Providence, USA., Gatsak D; Internal Medicine, State University of New York Downstate Medical Center, New York, USA., Moosa SA; Internal Medicine, St. John's Episcopal Hospital, Far Rockaway, USA.; Research, Bangladesh Medical Association of North America, New York, USA., Mozaffari MA; Internal Medicine, Corewell Health, East, Dearborn, USA., Imas AS; Internal Medicine, Mount Sinai Hospital, New York, USA., Miller R; Internal Medicine, Kings County Hospital Center, Brooklyn, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2023 Apr 14; Vol. 15 (4), pp. e37569. Date of Electronic Publication: 2023 Apr 14 (Print Publication: 2023).
DOI: 10.7759/cureus.37569
Abstrakt: Widespread uptake of the coronavirus disease 2019 (COVID-19) vaccinations has become the world's championed defense against the global pandemic. Four vaccines have been either approved or authorized for emergency use by the FDA, and at this time, over 13 billion doses of these vaccines have been administered around the world. Unfortunately, uncommon and sometimes unforeseen side effects such as small-vessel vasculitis have been reported. In this case report, we present a 74-year-old woman with a history of hypertension, type 2 diabetes mellitus, and hypothyroidism who developed microscopic polyangiitis (MPA) following the second dose of the Pfizer-BioNTech mRNA vaccine for COVID-19. The diagnosis of MPA was confirmed by a kidney biopsy. The autoimmune condition progressed to pericardial effusion and eventual cardiac tamponade, which is occasionally seen in the disease. In this patient's case, we suspect there to be a temporal association between mRNA COVID-19 vaccination and the development of MPA. Direct causation has not been determined.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Avalos et al.)
Databáze: MEDLINE