Post-Cardiac Arrest Syndrome.
| Autor: | Penketh J; Intensive care unit, Royal United Hospital, Bath., Nolan JP; Intensive care unit, Royal United Hospital, Bath.; Warwick Clinical Trials Unit, University of Warwick, Coventry, United Kingdom. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of neurosurgical anesthesiology [J Neurosurg Anesthesiol] 2023 Jul 01; Vol. 35 (3), pp. 260-264. Date of Electronic Publication: 2023 May 16. |
| DOI: | 10.1097/ANA.0000000000000921 |
| Abstrakt: | Post-cardiac arrest syndrome (PCAS) is a multicomponent entity affecting many who survive an initial period of resuscitation following cardiac arrest. This focussed review explores some of the strategies for mitigating the effects of PCAS following the return of spontaneous circulation. We consider the current evidence for controlled oxygenation, strategies for blood-pressure targets, the timing of coronary reperfusion, and the evidence for temperature control and treatment of seizures. Despite several large trials investigating specific strategies to improve outcomes after cardiac arrest, many questions remain unanswered. Results of some studies suggest that interventions may benefit specific subgroups of cardiac arrest patients, but the optimal timing and duration of many interventions remain unknown. The role of intracranial pressure monitoring has been the subject of only a few studies, and its benefits remain unclear. Research aimed at improving the management of PCAS is ongoing. Competing Interests: J.P.N. is the Editor-in-Chief of Resuscitation for which he receives an honorarium from Elsevier. J.P. has no conflicts of interest to declare. (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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