[Forensic chemical and chemicotoxicological examination of ricin poisoning by the HPLC-MS/MS method].

Autor:	Kalekin RA; Russian Center of Forensic Medical Examination, Moscow, Russia.; Peoples' Friendship University of Russia, Moscow, Russia., Barseghyan SS; Russian Center of Forensic Medical Examination, Moscow, Russia.; Peoples' Friendship University of Russia, Moscow, Russia., Volkova AA; Russian Center of Forensic Medical Examination, Moscow, Russia., Orlova AM; Russian Center of Forensic Medical Examination, Moscow, Russia., Akimova VD; Russian Center of Forensic Medical Examination, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Sudebno-meditsinskaia ekspertiza [Sud Med Ekspert] 2023; Vol. 66 (3), pp. 34-39.
DOI:	10.17116/sudmed20236603134
Abstrakt:	The Aim of the Study: Is to suggest the method of ricin determination in biological liquids during forensic medical and chemicotoxicological examination. This research describes the optimal conditions of sample processing of biological liquids, allowing to extract the components (ricinine and ricinoleic acid) of castor seeds. The recommended analysis conditions allow to perform research for 15 minutes by high resolution mass spectrometry method combined with high-value liquid chromatography on a chromato-mass spectrometer to detect ricinine and ricinoleic acid. The chromatographic (retention time) and mass-spectrometric parameters (mass spectra) were established for the exact high-quality determination of ricinine and ricinoleic acid.
Databáze:	MEDLINE
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