Case report: Sevelamer-associated colitis-a cause of pseudotumor formation with colon perforation and life-threatening bleeding.

Autor:	Fistrek Prlic M; Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia., Jelakovic M; Department of Gastroenterology, University Hospital Center Zagreb, Zagreb, Croatia., Brinar M; Department of Gastroenterology, University Hospital Center Zagreb, Zagreb, Croatia.; School of Medicine, University of Zagreb, Zagreb, Croatia., Grgic D; Department of Gastroenterology, University Hospital Center Zagreb, Zagreb, Croatia., Romic I; Department of Abdominal Surgery, University Hospital Center Zagreb, Zagreb, Croatia., Marusic Z; Department of Pathology, University Hospital Center Zagreb, Zagreb, Croatia., Ivandic E; Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia., Jelakovic B; Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia.; School of Medicine, University of Zagreb, Zagreb, Croatia., Vukovic Brinar I; Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia.; School of Medicine, University of Zagreb, Zagreb, Croatia., Krznaric Z; Department of Gastroenterology, University Hospital Center Zagreb, Zagreb, Croatia.; School of Medicine, University of Zagreb, Zagreb, Croatia.
Jazyk:	angličtina
Zdroj:	Frontiers in medicine [Front Med (Lausanne)] 2023 Apr 27; Vol. 10, pp. 1097469. Date of Electronic Publication: 2023 Apr 27 (Print Publication: 2023).
DOI:	10.3389/fmed.2023.1097469
Abstrakt:	Chronic kidney disease (CKD) is a very common chronic non-communicable disease. Phosphate and calcium metabolism disorders are one of the most common features of CKD. Sevelamer carbonate is the most widely used non-calcium phosphate binder. Gastrointestinal (GI) injury associated with sevelamer use is a documented adverse effect but is underrecognized as a cause of gastrointestinal symptoms in patients with CKD. We report a case of a 74-year-old woman taking low-dose sevelamer with serious gastrointestinal adverse effects causing colon rupture and severe gastrointestinal bleeding. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Fistrek Prlic, Jelakovic, Brinar, Grgic, Romic, Marusic, Ivandic, Jelakovic, Vukovic Brinar and Krznaric.)
Databáze:	MEDLINE
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