Histopathological analysis of vascular malformations.

Autor:	Pang C; Department of Surgical Biotechnology, Division of Surgery & Interventional Science, Faculty of Medical Sciences, University College London, London, UK.; Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK., Abu-Hanna J; Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK., Lim CS; Department of Surgical Biotechnology, Division of Surgery & Interventional Science, Faculty of Medical Sciences, University College London, London, UK.; Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK., Brookes J; Department of Surgical Biotechnology, Division of Surgery & Interventional Science, Faculty of Medical Sciences, University College London, London, UK.; Department of Interventional Radiology, Royal Free London NHS Foundation Trust, London, UK., Tsui J; Department of Surgical Biotechnology, Division of Surgery & Interventional Science, Faculty of Medical Sciences, University College London, London, UK.; Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK., Hamilton G; Department of Surgical Biotechnology, Division of Surgery & Interventional Science, Faculty of Medical Sciences, University College London, London, UK.; Department of Vascular Surgery, Royal Free London NHS Foundation Trust, London, UK., Onuba L; Department of Cellular Pathology, Royal Free London NHS Foundation Trust, London, UK., Deroide F; Department of Cellular Pathology, Royal Free London NHS Foundation Trust, London, UK.
Jazyk:	angličtina
Zdroj:	Phlebology [Phlebology] 2023 Jul; Vol. 38 (6), pp. 370-379. Date of Electronic Publication: 2023 May 12.
DOI:	10.1177/02683555231175022
Abstrakt:	Objective: To propose and develop a histopathological criteria to help diagnose vascular malformations. Methods: All patients who underwent surgical resection and had a confirmed histopathological diagnosis of vascular malformations from 01 March 2018-26 February 2020 were included. A criteria based on 10 parameters was developed to help diagnose vascular malformations. Discrepancies between clinical and histopathological diagnosis were evaluated. Results: A total of 18 cases were identified. There was a discrepancy between the clinical diagnosis and the initially reported histopathological diagnosis in 16 cases (88.9%). This was reduced to 7 (38.9%) and 6 cases (33.3%) with first and second time revised histopathological analysis using proposed criteria. Conclusions: The discrepancy between clinical and histopathological diagnoses of vascular malformations has highlighted the requirement of an agreed criteria for histopathologists to help formulate their diagnosis. The proposed criteria may be used as a guide in addressing this and guide treatment and improve clinical practice.
Databáze:	MEDLINE
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