Effect of an organic acid blend in Nile tilapia growth performance, immunity, gut microbiota, and resistance to challenge against francisellosis.

Autor: da Silva VG; Laboratory of Fish Bacteriology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil., Favero LM; Laboratory of Fish Bacteriology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil., Mainardi RM; Laboratory of Fish Bacteriology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil., Ferrari NA; Laboratory of Fish Bacteriology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil., Chideroli RT; Laboratory of Fish Bacteriology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil., Di Santis GW; Laboratory of Fish Bacteriology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil., de Souza FP; Department of Animal Science, State University of Londrina, Londrina, Paraná, Brazil., da Costa AR; Laboratory of Fish Bacteriology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil., Gonçalves DD; Department of Preventive Veterinary Medicine and Public Health, Paranaense University, Umuarama, PR, Brazil., Nuez-Ortin WG; Adisseo France SAS, Antony, Île-de-France, France., Isern-Subich MM; Adisseo France SAS, Antony, Île-de-France, France., de Oliveira-Junior AG; Department of Microbiology, State University of Londrina, Londrina, Paraná, Brazil., Lopera-Barrero NM; Department of Animal Science, State University of Londrina, Londrina, Paraná, Brazil., Pereira UP; Laboratory of Fish Bacteriology, Department of Preventive Veterinary Medicine, State University of Londrina, Londrina, Brazil. Electronic address: upaduapereira@uel.br.
Jazyk: angličtina
Zdroj: Research in veterinary science [Res Vet Sci] 2023 Jun; Vol. 159, pp. 214-224. Date of Electronic Publication: 2023 Apr 27.
DOI: 10.1016/j.rvsc.2023.04.019
Abstrakt: Organic acids (OAs) are a class of feed additives that have prophylactic and inhibitory properties against pathogenic bacteria. In this study, we investigated growth performance, innate immune response, gut microbiota, and disease resistance against Francisella orientalis F1 in Nile tilapia (Oreochromis niloticus) fed different doses of Bacti-nil®Aqua, a blend of short- and medium-chain OAs. For 21 days, 680 juvenile tilapias were fed a control diet or diets supplemented with a 0.3% (D3) or 0.5% (D5) OA blend. The feed conversion rate of fish fed the 0.5% enriched diet was considerably lower (p < 0.05) than that of the fish fed the basal diet. Lysozyme and serum bactericidal activities were significantly elevated following OA administration. After infection, no differences in the diversity and composition of gut microbiota were observed between the groups. After the bacterial challenge, the mortality was significantly lower in group D5 (p < 0.01). The diet supplemented with Bacti-nil®Aqua (Adisseo) improved the immune response and resistance of tilapia juveniles against F. orientalis infection. Thus, this OA blend could serve as a feed additive with good activity against F. orientalis.
Competing Interests: Declaration of Competing Interest The authors declare no conflict of interest.
(Published by Elsevier Ltd.)
Databáze: MEDLINE
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