Analysis of NIH K99/R00 Awards and the Career Progression of Awardees.

Autor:	Woitowich NC; Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Hengel SR; Department of Biology, Tufts University, Medford, MA, USA., Solis C; Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, FL, USA., Vilgalys TP; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA., Babdor J; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA, USA., Tyrrell DJ; Division of Molecular and Cellular Pathology, Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Jazyk:	angličtina
Zdroj:	BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 29. Date of Electronic Publication: 2023 Dec 29.
DOI:	10.1101/2023.01.26.525751
Abstrakt:	Many postdoctoral fellows and scholars who hope to secure tenure-track faculty positions in the United States apply to the National Institutes of Health (NIH) for a Pathway to Independence Award. This award has two phases (K99 and R00) and provides funding for up to five years. Using NIH data for the period 2006-2022, we report that ~230 K99 awards were made every year, representing up to ~$250 million annual investment. About 40% of K99 awardees were women and ~89% of K99 awardees went on to receive an R00 award annually. Institutions with the most NIH funding produced the most recipients of K99 awards and recruited the most recipients of R00 awards. The time between a researcher starting an R00 award and receiving a major NIH award (such as an R01) ranged between 4.6 and 7.4 years, and was significantly longer for women, for those who remained at their home institution, and for those hired by an institution that was not one of the 25 institutions with the most NIH funding. Shockingly, there has yet to be a K99 awardee at a historically Black college or university. We go on to show how K99 awardees flow to faculty positions, and to identify various factors that influence the future success of individual researchers and, therefore, also influence the composition of biomedical faculty at universities in the US. Competing Interests: Disclosures: D.J.T., T.V., S.R.H., C.S., J.B., and N.C.W have no competing interests. D.J.T. was a K99 recipient who transitioned to R00 in the 2021–2022 cycle and is included in this dataset.
Databáze:	MEDLINE
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