Acute exercise as a modifier of neocortical plasticity and aperiodic activity in the visual cortex.

Autor: Cadwallader CJ; School of Psychological Sciences, The Turner Institute for Brain and Mental Health, Monash University, Victoria, 3800, Australia. claire.cadwallader@monash.edu., Steiniger J; School of Psychological Sciences, The Turner Institute for Brain and Mental Health, Monash University, Victoria, 3800, Australia., Cooper PS; School of Psychological Sciences, The Turner Institute for Brain and Mental Health, Monash University, Victoria, 3800, Australia., Zhou SH; School of Psychology, James Cook University, Townsville, QLD, 4810, Australia., Hendrikse J; School of Psychological Sciences, The Turner Institute for Brain and Mental Health, Monash University, Victoria, 3800, Australia., Sumner RL; School of Pharmacy, The University of Auckland, Auckland, New Zealand., Kirk IJ; School of Psychology, The University of Auckland, Auckland, New Zealand., Chong TT; School of Psychological Sciences, The Turner Institute for Brain and Mental Health, Monash University, Victoria, 3800, Australia.; Department of Neurology, Alfred Health, Melbourne, VIC, 3004, Australia.; Department of Clinical Neurosciences, St Vincent's Hospital, Melbourne, VIC, 3065, Australia., Coxon JP; School of Psychological Sciences, The Turner Institute for Brain and Mental Health, Monash University, Victoria, 3800, Australia. james.coxon@monash.edu.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 May 09; Vol. 13 (1), pp. 7491. Date of Electronic Publication: 2023 May 09.
DOI: 10.1038/s41598-023-34749-w
Abstrakt: Long-term potentiation (LTP) is a form of neuroplasticity commonly implicated in mechanistic models of learning and memory. Acute exercise can boost LTP in the motor cortex, and is associated with a shift in excitation/inhibition (E:I) balance, but whether this extends to other regions such as the visual cortex is unknown. We investigated the effect of a preceding bout of exercise on LTP induction and the E:I balance in the visual cortex using electroencephalography (EEG). Young adults (N = 20, mean age = 24.20) engaged in 20 min of high-intensity interval training (HIIT) exercise and rest across two counterbalanced sessions. LTP was induced using a high frequency presentation of a visual stimulus; a "visual tetanus". Established EEG markers of visual LTP, the N1b and P2 component of the visual evoked potential, and an EEG-derived measure of the E:I balance, the aperiodic exponent, were measured before and after the visual tetanus. As expected, there was a potentiation of the N1b following the visual tetanus, with specificity to the tetanised stimulus, and a non-specific potentiation of the P2. These effects were not sensitive to a preceding bout of exercise. However, the E:I balance showed a late shift towards inhibition following the visual tetanus. A preceding bout of exercise resulted in specificity of this E:I balance shift to the tetanised stimulus, that was not seen following rest. This novel finding suggests a possible exercise-induced tuning of the visual cortex to stimulus details following LTP induction.
(© 2023. The Author(s).)
Databáze: MEDLINE
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