Association of mental health and negative life events with weight change in patients with overweight: A cohort study.

Autor: van den Hout WJ; Department of Public Health and Primary Care, Leiden University Medical Center, the Netherlands. Electronic address: w.j.van_den_hout@lumc.nl., Mook-Kanamori DO; Department of Public Health and Primary Care, Leiden University Medical Center, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, the Netherlands., van Peet PG; Department of Public Health and Primary Care, Leiden University Medical Center, the Netherlands., Büchner FL; Department of Public Health and Primary Care, Leiden University Medical Center, the Netherlands., Elzinga BM; Section of Clinical and Health Psychology, University of Leiden, the Netherlands., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, the Netherlands., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, the Netherlands., Numans ME; Department of Public Health and Primary Care, Leiden University Medical Center, the Netherlands.
Jazyk: angličtina
Zdroj: Journal of affective disorders [J Affect Disord] 2023 Aug 01; Vol. 334, pp. 325-331. Date of Electronic Publication: 2023 May 07.
DOI: 10.1016/j.jad.2023.05.001
Abstrakt: Background: It is unclear to what extent mental health and negative life events (NLEs) contribute to weight change in patients with overweight. This study aimed to evaluate the association of anxiety, depression, NLEs and quality of life (QoL) with weight change over ten years in middle-aged individuals with overweight.
Methods: Population-based cohort study of 2889 middle-aged men and women with a body mass index ≥27 kg/m 2 . Relative weight change over ten years was defined as weight loss (≤- 5 %), stable weight (between >- 5 % and <5 %) or weight gain (≥5 %). At baseline, participants reported anxiety symptoms, depressive symptoms, recent (last year) and distant (lifetime) NLEs, and a mental component summary of QoL. With multinomial logistic regression adjusting for potential confounding, we examined the association of mental health and NLEs with weight change after a median (25th, 75th percentiles) follow-up of 9.7 (9.0-10.5) years.
Results: In 51 % participants weight was stable, 33 % participants lost weight and 17 % gained weight. Mild (odds ratio 1.36; 95 % confidence interval 1.05-1.75), and moderate to very severe depressive symptoms (1.43; 0.97-2.12) and four or more distant NLEs (1.35; 1.10-1.67) were associated with weight gain. Anxiety symptoms, the mental component summary of QoL were not associated with either weight gain or weight loss.
Limitations: Due to the observational design residual confounding cannot be excluded.
Conclusion: Our study suggests that depressive symptoms or having experienced distant NLEs are associated with weight gain over time in middle-aged individuals with overweight. These subgroups might benefit from proactive attention from their health care providers.
Competing Interests: Declaration of competing interest None.
(Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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