Guillain-Barre Syndrome, a Leptomeningeal Metastasis Mimic, in a Patient With Metastatic Breast Carcinoma.

Autor:	Torrente N; Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA., Boldig K; Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA., Stack A; Hematology/Oncology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA., Gharia B; Hematology/Medical Oncology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Apr 03; Vol. 15 (4), pp. e37079. Date of Electronic Publication: 2023 Apr 03 (Print Publication: 2023).
DOI:	10.7759/cureus.37079
Abstrakt:	Leptomeningeal metastasis (LM) is an outcome associated with a terminal prognosis for a patient with metastatic cancer. Symptoms associated with this type of cancer progression can be subtle and nonspecific. Evaluation of LM occurs with a lumbar puncture (LP) and magnetic resonance imaging (MRI). Guillain-Barre Syndrome (GBS) can present with a similar presentation of neurological symptoms to LM. Additionally, both disease states may present with similar MRI findings. The LP can be an important diagnostic evaluation to differentiate LM and GBS. However, an LP may be unremarkable in both disease states. Therefore, a comprehensive assessment of the patient based on clinical history, physical examination, laboratory, and radiologic evaluation is essential for prompt diagnosis and treatment. We present a patient with metastatic breast cancer that presented with generalized weakness. Thorough evaluation allowed the diagnosis and treatment of GBS. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Torrente et al.)
Databáze:	MEDLINE
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