Incidence of biopsy-proven giant cell arteritis (GCA) in South Australia 2014-2020.

Autor:	Ninan J; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, Northern Adelaide Local Health Network, Modbury, SA, Australia., Ruediger C; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, SA, Australia., Dyer KA; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, SA, Australia., Dodd T; SA Pathology, Adelaide, SA, Australia., Black RJ; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, SA, Australia.; Rheumatology Unit, Royal Adelaide Hospital, Adelaide, SA, Australia., Lyne S; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, SA, Australia., Shanahan EM; School of Medicine, Flinders University, Bedford Park, SA, Australia.; Rheumatology Unit, Southern Adelaide Local Health Network, Bedford Park, SA, Australia., Proudman SM; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, Royal Adelaide Hospital, Adelaide, SA, Australia., Lester S; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, SA, Australia., McNeil J; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, Northern Adelaide Local Health Network, Modbury, SA, Australia., Hill CL; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.; Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, SA, Australia.; Rheumatology Unit, Royal Adelaide Hospital, Adelaide, SA, Australia.
Jazyk:	angličtina
Zdroj:	Frontiers in medicine [Front Med (Lausanne)] 2023 Apr 20; Vol. 10, pp. 1173256. Date of Electronic Publication: 2023 Apr 20 (Print Publication: 2023).
DOI:	10.3389/fmed.2023.1173256
Abstrakt:	Objective: To determine the incidence of biopsy proven giant cell arteritis (GCA) in South Australia. Methods: Patients with biopsy-proven GCA were identified from pathology reports of temporal artery biopsies at state-based pathology laboratories, from 1 January 2014 to 31 December 2020. Incidence rates for biopsy-proven GCA were calculated using Australian Bureau of Statistics data for South Australian population sizes by age, sex, and calendar year. Seasonality was analyzed by cosinor analysis. Results: There were 181 cases of biopsy-proven GCA. The median age at diagnosis of GCA was 76 years (IQR 70, 81), 64% were female. The estimated population incidence for people over 50 was 5.4 (95% CI 4.7, 6.1) per 100,000-person years. The female: male incidence ratio was 1.6 (95% CI 1.2, 2.2). There was no ordinal trend in GCA incidence rates by calendar year ( p = 0.29). The incidence was, on average, highest in winter, but not significantly ( p = 0.35). A cosinor analysis indicated no seasonal effect ( p = 0.52). Conclusion: The incidence of biopsy-proven GCA remains low in Australia. A higher incidence was noted compared to an earlier study. However, differences in ascertainment and methods of GCA diagnosis may have accounted for the change. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Ninan, Ruediger, Dyer, Dodd, Black, Lyne, Shanahan, Proudman, Lester, McNeil and Hill.)
Databáze:	MEDLINE
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