Hepatitis C Virus in Pregnancy: An Opportunity to Test and Treat.
| Autor: | Fogel RS; University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA 15213, USA., Chappell CA; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213, USA; Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA 15213, USA. Electronic address: chappellca@upmc.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Obstetrics and gynecology clinics of North America [Obstet Gynecol Clin North Am] 2023 Jun; Vol. 50 (2), pp. 363-373. |
| DOI: | 10.1016/j.ogc.2023.02.008 |
| Abstrakt: | With the advent of safe and well-tolerated direct-acting antiviral (DAA) medications for hepatitis C virus (HCV), disease eradication is on the horizon. However, as the rate of HCV infection among women of childbearing potential continues to rise due to the ongoing opioid epidemic in the United States, perinatal transmission of HCV presents an increasingly difficult barrier. Without the ability to treat HCV during pregnancy, complete eradication is unlikely. In this review, we discuss the current epidemiology of HCV in the United States, the current management strategy for HCV in pregnancy, as well as the potential for future use of DAAs in pregnancy. (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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