The influence of nutrition on white matter development in preterm infants: a scoping review.

Autor: Janson E; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Willemsen MF; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Faculty of Medicine, Utrecht University, Utrecht, The Netherlands., Van Beek PE; Department of Neonatology, Máxima Medical Center, Veldhoven, The Netherlands., Dudink J; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Van Elburg RM; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Pediatrics, Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, The Netherlands., Hortensius LM; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Tam EWY; Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada., de Pipaon MS; Neonatology, Instituto de Investigación Sanitaria, La Paz University Hospital-IdiPAZ (Universidad Autonoma), Madrid, Spain., Lapillonne A; Department of Neonatology, Necker-Enfants Malades Hospital, University of Paris, Paris, France., de Theije CGM; Department for Developmental Origins of Disease, University Medical Center Utrecht Brain Center and Wilhelmina Children's Hospital, Utrecht University, 3508 AB, Utrecht, The Netherlands., Benders MJNL; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., van der Aa NE; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. N.vanderAa@umcutrecht.nl.; University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands. N.vanderAa@umcutrecht.nl.
Jazyk: angličtina
Zdroj: Pediatric research [Pediatr Res] 2023 May 05. Date of Electronic Publication: 2023 May 05.
DOI: 10.1038/s41390-023-02622-1
Abstrakt: White matter (WM) injury is the most common type of brain injury in preterm infants and is associated with impaired neurodevelopmental outcome (NDO). Currently, there are no treatments for WM injury, but optimal nutrition during early preterm life may support WM development. The main aim of this scoping review was to assess the influence of early postnatal nutrition on WM development in preterm infants. Searches were performed in PubMed, EMBASE, and COCHRANE on September 2022. Inclusion criteria were assessment of preterm infants, nutritional intake before 1 month corrected age, and WM outcome. Methods were congruent with the PRISMA-ScR checklist. Thirty-two articles were included. Negative associations were found between longer parenteral feeding duration and WM development, although likely confounded by illness. Positive associations between macronutrient, energy, and human milk intake and WM development were common, especially when fed enterally. Results on fatty acid and glutamine supplementation remained inconclusive. Significant associations were most often detected at the microstructural level using diffusion magnetic resonance imaging. Optimizing postnatal nutrition can positively influence WM development and subsequent NDO in preterm infants, but more controlled intervention studies using quantitative neuroimaging are needed. IMPACT: White matter brain injury is common in preterm infants and associated with impaired neurodevelopmental outcome. Optimizing postnatal nutrition can positively influence white matter development and subsequent neurodevelopmental outcome in preterm infants. More studies are needed, using quantitative neuroimaging techniques and interventional designs controlling for confounders, to define optimal nutritional intakes in preterm infants.
(© 2023. The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc.)
Databáze: MEDLINE
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