Phytochemical Profiling, In-vitro Antioxidant and Cytotoxic Effects of Luisia tenuifolia Extracts Against Human Skin Squamous Carcinoma.
Autor: | Sethuraman SP; Department of Pharmacognosy, Faculty of Medicine and Health Sciences, SRM College of Pharmacy, SRM Institute of Science & Technology, SRM Nagar, Kattankulathur, Kanchipuram, 603203, Chennai, TN, India. sakthips1@srmist.edu.in., Ramachandran KP; Department of Pharmacognosy, Faculty of Medicine and Health Sciences, SRM College of Pharmacy, SRM Institute of Science & Technology, SRM Nagar, Kattankulathur, Kanchipuram, 603203, Chennai, TN, India. |
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Jazyk: | angličtina |
Zdroj: | Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2024 Jan; Vol. 196 (1), pp. 400-416. Date of Electronic Publication: 2023 May 04. |
DOI: | 10.1007/s12010-023-04521-x |
Abstrakt: | The present study establishes the phytochemical screening, TLC profiling, in-vitro radical scavenging, and anticancer activities in the successive extracts of whole plant of L. tenuifolia Blume. The preliminary phytochemical screening followed by quantitative estimation of bioactive secondary metabolites revealed higher abundance of phenolic (13.22 ± 0.21 mg GAE/g of extract), flavonoid (8.09 ± 0.13 mg QE/g of extract), and tannin (7.53 ± 0.08 mg GAE/g of extract) contents in ethyl acetate extract of L. tenuifolia which might be attributed to the difference in the polarity and efficacy of the solvents used in successive Soxhlet extraction. Antioxidant activity assessed by DPPH assay and ABTS assay revealed that the ethanol extract exhibited the highest radical scavenging activity with an IC (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.) |
Databáze: | MEDLINE |
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