Patient-reported mental health and well-being trajectories in oncology patients during radiation therapy: an exploratory retrospective cohort analysis using the Ontario Cancer Registry.

Autor: Kwon JY; School of Nursing, University of Victoria, HSD Building A402A, PO Box 1700 STN CSC, Victoria, BC, V8W 2Y2, Canada. jykn1@uvic.ca.; Institute on Aging and Lifelong Health, Victoria, Canada. jykn1@uvic.ca., Kopec J; School of Population and Public Health, University of British Columbia, Vancouver, Canada., Sutherland JM; Centre for Health Services and Policy Research, School of Population and Public Health, University of British Columbia, Vancouver, Canada., Lambert LK; Nursing and Allied Health Research and Knowledge Translation, BC Cancer, Vancouver, Canada.; School of Nursing, University of British Columbia, Vancouver, Canada., Anis AH; School of Population and Public Health, University of British Columbia, Vancouver, Canada.; Centre for Health Evaluation and Outcome Sciences, Providence Research, Vancouver, Canada., Sawatzky R; Centre for Health Evaluation and Outcome Sciences, Providence Research, Vancouver, Canada.; School of Nursing, Trinity Western University, Langley, Canada.; Sahlgrenska Academy, University of Gothenburg, 40530, Gothenburg, Sweden.
Jazyk: angličtina
Zdroj: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation [Qual Life Res] 2023 Oct; Vol. 32 (10), pp. 2899-2909. Date of Electronic Publication: 2023 May 04.
DOI: 10.1007/s11136-023-03430-0
Abstrakt: Purpose: Mental health and well-being trajectories are not expected to be homogeneous in diverse clinical populations. This exploratory study aims to identify subgroups of patients with cancer receiving radiation therapy who have different mental health and well-being trajectories, and examine which socio-demographic, physical symptoms, and clinical variables are associated with such trajectories.
Methods: Retrospective analysis of radiation therapy patients diagnosed with cancer in 2017 was conducted using data from the Ontario Cancer Registry (Canada) and linked with administrative health data. Mental health and well-being were measured using items from the Edmonton Symptom Assessment System-revised questionnaire. Patients completed up to 6 repeated measurements. We used latent class growth mixture models to identify heterogeneous mental health trajectories of anxiety, depression, and well-being. Bivariate multinomial logistic regressions were conducted to explore variables associated with the latent classes (subgroups).
Results: The cohort (N = 3416) with a mean age of 64.5 years consisted of 51.7% females. Respiratory cancer was the most common diagnosis (30.4%) with moderate to severe comorbidity burden. Four latent classes with distinct anxiety, depression, and well-being trajectories were identified. Decreasing mental health and well-being trajectories are associated with being female; living in neighborhoods with lower income, greater population density, and higher proportion of foreign-born individuals; and having higher comorbidity burden.
Conclusions: The findings highlight the importance of considering social determinants of mental health and well-being, in addition to symptoms and clinical variables, when providing care for patients undergoing radiation therapy.
(© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje