A New Powder Dressing for Management of Chronic Venous Ulcers.

Autor:	Mahmood BA; Plastic and Reconstructive Surgery Department, Faculty of Medicine, Helwan University, Cairo, Egypt., ElSayed EH; Plastic and Reconstructive Surgery Department, Faculty of Medicine (Girls), Al-Azhar University, Cairo, Egypt., Abd Elghany SM; Plastic Surgery Department, Faculty of Medicine, Al-Azhar University, Damitta, Egypt., Elnaggar DF; Plastic and Reconstructive Surgery Department, Faculty of Medicine, Helwan University, Cairo, Egypt., Youssef HAA; General Surgery Department, Faculty of Medicine (Girls), Al-Azhar University, Cairo, Egypt., Abdelmaksoud SM; Plastic and Reconstructive Surgery Department, Faculty of Medicine, Port-Said University, Port-Said, Egypt.
Jazyk:	angličtina
Zdroj:	Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2023 Jul 01; Vol. 49 (7), pp. 664-668. Date of Electronic Publication: 2023 Apr 25.
DOI:	10.1097/DSS.0000000000003812
Abstrakt:	Background: A new powder dressing (TPD) is a methacrylate-based powder formulation that transforms in situ into a shape-retentive matrix upon hydration to create optimum moist wound healing conditions. The following randomized, controlled, clinical study aimed to evaluate the role of TPD in the management of chronic venous ulcers (CVU). Methods: The randomized controlled prospective study enrolled 60 CVU patients. After randomization, patients in the treatment group ( n = 30) were treated with TPD, whereas those in the control group ( n = 30) received conventional compression dressing therapy. Results: After treatment, patients in the TPD group had significantly higher rates of complete ulcer healing at 12 weeks (43.3% vs 10.0%, p = .004) and 24 weeks (86.7% vs 40.0%, p = .001) when compared with conventional dressing group. Moreover, patients in the TP dressing group had significantly shorter time to complete ulcer healing [mean (95% CI): 16.7 (14.1-19.3) versus 37.0 (30.8-43.2) weeks, p = .001]. In addition, patients in the TPD group had significantly fewer number of dressings, less severe pain after dressing, and lower need for systemic analgesics. Conclusion: Use of TPD in management of CVUs was associated with significantly higher healing rates, shorter duration to healing, and lower pain. (Copyright © 2023 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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