Breathless nights and heart flutters: Understanding the relationship between obstructive sleep apnea and atrial fibrillation.
Autor: | Mills EW; Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address: ewmills@partners.org., Antman EM; Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts., Javaheri S; Division of Sleep Medicine, Brigham and Women's Hospital, Boston, Massachusetts. |
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Jazyk: | angličtina |
Zdroj: | Heart rhythm [Heart Rhythm] 2023 Sep; Vol. 20 (9), pp. 1267-1273. Date of Electronic Publication: 2023 Apr 29. |
DOI: | 10.1016/j.hrthm.2023.04.022 |
Abstrakt: | There is an extraordinary and increasing global burden of atrial fibrillation (AF) and obstructive sleep apnea (OSA), two conditions that frequently accompany one another and that share underlying risk factors. Whether a causal pathophysiologic relationship connects OSA to the development and/or progression of AF, or whether shared risk factors promote both conditions, is unproven. With increasing recognition of the importance of controlling AF-related risk factors, numerous observational studies now highlight the potential benefits of OSA treatment in AF-related outcomes. Physicians are regularly faced with caring for this important and increasing population of patients despite a paucity of clinical guidance on the topic. Here, we review the clinical epidemiology and pathophysiology of AF and OSA with a focus on key clinical studies and major outstanding questions that should be addressed in future studies. (Copyright © 2023 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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