Cognitive functions and patterns of brain activity in patients after simultaneous coronary and carotid artery revascularization.

Autor:	Tarasova I; Department of Clinical Cardiology, State Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia., Trubnikova O; Department of Clinical Cardiology, State Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia., Kupriyanova DS; Department of Clinical Cardiology, State Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia., Maleva O; Department of Clinical Cardiology, State Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia., Syrova I; Department of Clinical Cardiology, State Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia., Kukhareva I; Department of Clinical Cardiology, State Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia., Sosnina A; Department of Clinical Cardiology, State Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia., Tarasov R; Department of Cardiac and Vascular Surgery, State Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia., Barbarash O; Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia.
Jazyk:	angličtina
Zdroj:	Frontiers in human neuroscience [Front Hum Neurosci] 2023 Apr 12; Vol. 17, pp. 996359. Date of Electronic Publication: 2023 Apr 12 (Print Publication: 2023).
DOI:	10.3389/fnhum.2023.996359
Abstrakt:	Background: On-pump coronary artery bypass grafting (CABG) is associated with a high risk of neurological complications in patients with severe carotid stenosis. Moreover, early postoperative cognitive dysfunction (POCD) incidence remains high in patients undergoing simultaneous coronary and carotid surgery. Recent studies have shown that even moderate carotid stenosis (≥50%) is associated with postoperative cognitive decline after CABG. Data on brain health in the postoperative period of simultaneous coronary and carotid surgery are limited. Objectives: This study aimed to analyze early postoperative changes in the cognitive function and patterns of brain electrical activity in patients after simultaneous coronary and carotid artery revascularization. Materials and Methods: Between January 2017 and December 2020, consecutive patients were assigned to on-pump CABG with or without carotid endarterectomy (CEA) according to clinical indications. An extended neuropsychological and electroencephalographic (EEG) assessment was performed before surgery and at 7-10 days after CABG or CABG + CEA. Results: A total of 100 patients were included [median age 59 (55; 65), 95% men, MMSE 27 (26; 28)], and among these, 46 underwent CEA. POCD was diagnosed in 29 (63.0%) patients with CABG + CEA and in 32 (59.0%) patients with isolated CABG. All patients presented with a postoperative theta power increase. However, patients with CABG + right-sided CEA demonstrated the most pronounced theta power increase compared to patients with isolated CABG. Conclusion: The findings of our study show that patients with CABG + CEA and isolated CABG have comparable POCD incidence; however, patients with CABG + right-sided CEA presented with lower brain activity. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Tarasova, Trubnikova, Kupriyanova, Maleva, Syrova, Kukhareva, Sosnina, Tarasov and Barbarash.)
Databáze:	MEDLINE
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