Bempedoic acid: what prospective uses?

Autor: Jacomelli I; Department of Cardiology, Policlinico Casilino, Via Casilina 1049, 00169 Rome, Italy., Monzo L; Department of Cardiology, Policlinico Casilino, Via Casilina 1049, 00169 Rome, Italy.; Centre d'investigation Cliniques Plurithématique, Universitè de Lorraine INSERM, Nancy, France., Panattoni G; Department of Cardiology, Policlinico Casilino, Via Casilina 1049, 00169 Rome, Italy., Lanzillo C; Department of Cardiology, Policlinico Casilino, Via Casilina 1049, 00169 Rome, Italy., Rebecchi M; Department of Cardiology, Policlinico Casilino, Via Casilina 1049, 00169 Rome, Italy., Calò L; Department of Cardiology, Policlinico Casilino, Via Casilina 1049, 00169 Rome, Italy.
Jazyk: angličtina
Zdroj: European heart journal supplements : journal of the European Society of Cardiology [Eur Heart J Suppl] 2023 Apr 26; Vol. 25 (Suppl C), pp. C109-C111. Date of Electronic Publication: 2023 Apr 26 (Print Publication: 2023).
DOI: 10.1093/eurheartjsupp/suad012
Abstrakt: There is still the need to lower LDL-c, although the use of statins, ezetimibe and proprotein convertase subtilisin/kexin type 9. Patients with atherosclerotic cardiovascular disease and/or familial hypercholesterolaemia are treated with statins at maximum tolerated dose, with or without further lipid-lowering drugs, but very often, we can't reach the goal, so bempedoic acid treatment lead to a significant reduction in low-density lipoprotein cholesterol, in different groups of patients, with a favourable safety profile.
Competing Interests: Conflict of interest: None declared.
(© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.)
Databáze: MEDLINE