Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines.

Autor: Olatunde OZ; Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fujian 350025, China.; University of Chinese Academy of Sciences, Beijing 101408, China., Yong J; Xiamen Institute of Rare-Earth Materials, Chinese Academy of Sciences, Xiamen 361021, China., Lu C; Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fujian 350025, China.; Xiamen Institute of Rare-Earth Materials, Chinese Academy of Sciences, Xiamen 361021, China.; University of Chinese Academy of Sciences, Beijing 101408, China.
Jazyk: angličtina
Zdroj: ACS omega [ACS Omega] 2023 Apr 12; Vol. 8 (16), pp. 14662-14664. Date of Electronic Publication: 2023 Apr 12 (Print Publication: 2023).
DOI: 10.1021/acsomega.3c00544
Abstrakt: A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC 50 's of 193.5 μM for 24 h and 154.6 μM for 48 h.
Competing Interests: The authors declare no competing financial interest.
(© 2023 The Authors. Published by American Chemical Society.)
Databáze: MEDLINE