Nutrition intake in critically ill patients with coronavirus disease (COVID-19): A nationwide, multicentre, observational study in Argentina.

Autor: Chapela SP; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina; Universidad de Buenos Aires, Facultad de Medicina, Departamento de Bioquímica, Buenos Aires, Argentina., Manzanares W; Chair of intensive Medicina, Faculty of Medicine, Universidad de la Republica, Montevideo, Uruguay., Quesada E; Chapter of Dieticians in ICU (CALINU), of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Reberendo MJ; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Baccaro F; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Aversa I; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Kecskes CE; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Magnifico L; Chapter of Dieticians in ICU (CALINU), of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Gonzalez V; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina; Universidad Católica de Córdoba, Master's in Obesology, Córdoba, Argentina; Universidad Nacional de Córdoba, Faculty of Chemical Sciences, Master's in Food Science and Technology, Córdoba, Argentina., Bolzicco D; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Baraglia N; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Navarrete P; Chapter of Dieticians in ICU (CALINU), of the Argentinian Society of Intensive Care Medicine (SATI), Argentina; Universidad Juan Agustín Masa, Professional Practice, Mendoza, Argentina., Manrique E; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Cascaron MF; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Dietrich A; Chapter of Dieticians in ICU (CALINU), of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Asparch J; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Peralta LB; Chapter of Dieticians in ICU (CALINU), of the Argentinian Society of Intensive Care Medicine (SATI), Argentina; Universidad Austral, Faculty of Biomedical Sciences, Food and Nutrition Assessment of Adults, Buenos Aires, Argentina., Galletti C; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Capria ML; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Lombi Y; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Rodriguez MC; Chapter of Dieticians in ICU (CALINU), of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Luna CE; Chapter of Dieticians in ICU (CALINU), of the Argentinian Society of Intensive Care Medicine (SATI), Argentina., Martinuzzi ALN; Committee of Nutrition Support and Metabolism (COSONUME) of the Argentinian Society of Intensive Care Medicine (SATI), Argentina. Electronic address: andres.martinuzzi@nutrihome.com.ar.
Jazyk: angličtina
Zdroj: Endocrinologia, diabetes y nutricion [Endocrinol Diabetes Nutr (Engl Ed)] 2023 Apr; Vol. 70 (4), pp. 245-254.
DOI: 10.1016/j.endien.2023.03.016
Abstrakt: Introduction: In 2020 the pandemic caused by SARS-COV-2 demanded an enormous number of healthcare resources in order to guarantee adequate treatment and support for those patients. This study aims to assess caloric and protein intake and evaluate its associations with relevant clinical outcomes in critically ill with coronavirus disease (COVID-19) patients.
Methods: A nationwide, multicentre prospective observational study including twelve Argentinian intensive care units (ICUs,) was conducted between March and October 2020.
Inclusion Criteria: Adult ICU patients>18 years admitted to the ICU with COVID-19 diagnosis and mechanical ventilation for at least 48h. Statistical analysis was carried out using IBM-SPSS© 24 programme.
Results: One hundred and eighty-five patients were included in the study. Those who died had lower protein intake (0.73g/kg/day (95% confidence interval (CI) 0.70-0.75 vs 0.97g/kg/day (CI 0.95-0.99), P<0.001), and lower caloric intake than those who survived (12.94kcal/kg/day (CI 12.48-13.39) vs 16.47kcal/kg/day (CI 16.09-16.8), P<0.001). A model was built, and logistic regression showed that factors associated with the probability of achieving caloric and protein intake, were the early start of nutritional support, modified NUTRIC score higher than five points, and undernutrition (Subjective Global Assessment B or C). The patients that underwent mechanical ventilation in a prone position present less caloric and protein intake, similar to those with APACHE II>18.
Conclusions: Critically ill patients with COVID-19 associated respiratory failure requiring mechanical ventilation who died in ICU had less caloric and protein intake than those who survived. Early start on nutritional support and undernutrition increased the opportunity to achieve protein and caloric goals, whereas the severity of disease and mechanical ventilation in the prone position decreased the chance to reach caloric and protein targets.
(Copyright © 2023 SEEN and SED. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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