Black and Yellow Soybean Consumption Prevents High-Fat Diet-Induced Obesity by Regulating Lipid Metabolism in C57BL/6 Mice.

Autor: Jeong EW; Department of Food and Nutrition, Hanyang University, Seoul 04763, Republic of Korea., Dhungana SK; Department of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration, Miryang 50424, Republic of Korea., Yang YS; Department of Food and Nutrition, Hanyang University, Seoul 04763, Republic of Korea., Baek Y; Department of Food and Nutrition, Hanyang University, Seoul 04763, Republic of Korea., Seo JH; Department of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration, Miryang 50424, Republic of Korea., Kang BK; Department of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration, Miryang 50424, Republic of Korea., Jung CS; Department of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration, Miryang 50424, Republic of Korea., Han SI; Department of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration, Miryang 50424, Republic of Korea., Lee HG; Department of Food and Nutrition, Hanyang University, Seoul 04763, Republic of Korea.
Jazyk: angličtina
Zdroj: Evidence-based complementary and alternative medicine : eCAM [Evid Based Complement Alternat Med] 2023 Apr 18; Vol. 2023, pp. 6139667. Date of Electronic Publication: 2023 Apr 18 (Print Publication: 2023).
DOI: 10.1155/2023/6139667
Abstrakt: To evaluate the antiobesity effects of yellow and black soybean, C57BL/6 mice were provided with a normal diet, high-fat diet, HFD-containing yellow soybean powder (YS), and black soybean powder (BS) for six weeks. Compared with the HFD group, both YS and BS decreased body weight by 30.1% and 37.2% and fat in tissue by 33.3% and 55.8%, respectively. Simultaneously, both soybeans significantly reduced the serum triglyceride and total cholesterol levels and regulated the lipogenic mRNA expressions of Ppar γ , Acc, and Fas genes in the liver, supporting reduced body adiposity. Furthermore, BS significantly increased Pgc-1 α and Ucp1 mRNA expression levels in epididymal adipose tissue, indicating thermogenesis is the key mechanism of BS. Taken together, our findings suggest that both soybeans prevent high-fat diet-induced obesity in mice by regulating lipid metabolism, and BS, in particular, has a greater antiobesity potential than YS.
Competing Interests: The authors declare that there are no conflicts of interest to declare.
(Copyright © 2023 Eun Woo Jeong et al.)
Databáze: MEDLINE
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