Spontaneous facial hematoma induced by vitamin K antagonist therapy: a rare case report.

Autor: Mrabet A; Department of Cardiology, Mohamed VI University Hospital Center, Mohamed I University, Oujda, Morocco., Boulouiz S; Department of Cardiology, Mohamed VI University Hospital Center, Mohamed I University, Oujda, Morocco., Bilal M; Department of Cardiology, Mohamed VI University Hospital Center, Mohamed I University, Oujda, Morocco., El Ouafi N; Department of Cardiology, Mohamed VI University Hospital Center, Mohamed I University, Oujda, Morocco., Bazid Z; Department of Cardiology, Mohamed VI University Hospital Center, Mohamed I University, Oujda, Morocco.
Jazyk: angličtina
Zdroj: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2023 Apr 03; Vol. 85 (4), pp. 1141-1144. Date of Electronic Publication: 2023 Apr 03 (Print Publication: 2023).
DOI: 10.1097/MS9.0000000000000358
Abstrakt: The benefits of anti-vitamin K drugs have been demonstrated in several indications; however, it is always counterbalanced by an increased risk of bleeding, that can occur in different areas. Facial hematoma is a rare bleeding complication to our knowledge, this is the first report of a rapidly expanding atraumatic facial hematoma secondary to vitamin K antagonist over coagulation.
Case Presentation: The authors report the case of an 80-year-old woman with a medical history of hypertension, and pulmonary embolism after 15 days of immobilization following a hip fracture treated surgically 3 years earlier, who has been on vitamin K antagonist therapy since then, without any follow-up, came into our emergency department complaining of a sudden onset of progressive left facial swelling for one day, and vision loss in her left eye. Her blood investigations revealed a high international normalized ratio of prothrombin up to 10. A computed tomography scan exposing face, orbit, and oromaxillofacial area objectived spontaneously hyperdense collection in the left masticator space suggestive of an hematoma. An intraoral incision was done by oromaxillar surgeons, and drainage were performed with a favorable evolution.
Clinical Discussion: In this mini review, the authors aim to describe this rare complication and to insist on the necessity of regular follow-up with international normalized ratio values and early warning signs of bleeding to prevent such fatal complications.
Conclusion: Immediate recognition and management of such complication is very important to avoid complications.
Competing Interests: None of the contributing authors have any conflict of interest, including specific financial interests or relationships and affiliations relevant to the subject matter or materials discussed in the manuscript.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.
(Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze: MEDLINE