An atypical presentation of granulomatosis with polyangiitis: A case report.

Autor:	Maqbool U; Department of ENT, King Edward Medical University Lahore, Pakistan., Maqbool A; Department of Medicine, Rashid Latif Medical College Lahore, Pakistan., Maqbool A; Department of Medicine, CMH Medical College Lahore, Pakistan., Qadeer A; Department of Medicine, King Edward Medical University Lahore, Pakistan., Mehmood MF; Department of Medicine, King Edward Medical University Lahore, Pakistan., Loon M; Department of Medicine, King Edward Medical University Lahore, Pakistan.
Jazyk:	angličtina
Zdroj:	Radiology case reports [Radiol Case Rep] 2023 Apr 14; Vol. 18 (6), pp. 2245-2248. Date of Electronic Publication: 2023 Apr 14 (Print Publication: 2023).
DOI:	10.1016/j.radcr.2023.03.023
Abstrakt:	Granulomatosis with polyangiitis (GPA) is a systemic vasculitis that is associated with antineutrophil cytoplasmic antibodies (c-ANCA). It classically presents with sinonasal, pulmonary and renal involvement. We are presenting a case of a 32-year-old male who presented with septal perforation, crusting and nasal obstruction. He had been operated on twice for sinonasal polyposis. Relevant investigations revealed that he was actually suffering from GPA. The patient was started on remission induction therapy. A combination of methotrexate and prednisolone was started with a 2-weekly follow-up. The patient had experienced his symptoms for 2 years before presentation. This case highlights the importance of correlating ENT and pulmonary symptoms to reach the correct diagnosis. (© 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)
Databáze:	MEDLINE
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