Short-Term L-Citrulline Supplementation Does Not Affect Inspiratory Muscle Oxygenation and Respiratory Performance in Older Adults.

Autor: Theodorou AA; Department of Life Sciences, School of Sciences, European University Cyprus, 1516 Nicosia, Cyprus., Chatzinikolaou PN; Department of Physical Education and Sport Science at Serres, Aristotle University of Thessaloniki, 61122 Thessaloniki, Greece., Margaritelis NV; Department of Physical Education and Sport Science at Serres, Aristotle University of Thessaloniki, 61122 Thessaloniki, Greece., Christodoulou F; Department of Life Sciences, School of Sciences, European University Cyprus, 1516 Nicosia, Cyprus., Tsatalas T; Department of Life Sciences, School of Sciences, European University Cyprus, 1516 Nicosia, Cyprus.; Department of Physical Education & Sport Science, University of Thessaly, 42100 Trikala, Greece., Paschalis V; School of Physical Education and Sport Science, National and Kapodistrian University of Athens, 17237 Athens, Greece.
Jazyk: angličtina
Zdroj: Nutrients [Nutrients] 2023 Apr 18; Vol. 15 (8). Date of Electronic Publication: 2023 Apr 18.
DOI: 10.3390/nu15081951
Abstrakt: In sports nutrition, nitric oxide (NO ) precursors such as L-citrulline are widely used to enhance NO bioavailability, which is considered an ergogenic aid. Our study aimed to examine the effect of short-term L-citrulline supplementation on respiratory muscles' performance, fatigue, and oxygenation in older adults. Fourteen healthy older males took 6 g of L-citrulline or a placebo for seven days in a double-blind crossover design. Pulmonary function via spirometry (i.e., forced expired volume in 1 s (FEV 1 ), forced vital capacity (FVC), and their ratio)), fractional exhaled nitric oxide (NO ), maximal inspiratory pressure (MIP), rate of perceived exertion, and sternocleidomastoid muscle oxygenation (i.e., oxyhemoglobin (Δ[O 2 Hb]) and de-oxyhemoglobin (Δ[HHb]), total hemoglobin concentration (Δ[tHb]), and tissue saturation index (TSI%)) were evaluated at baseline, after seven days of L-citrulline supplementation, and after incremental resistive breathing to task failure of the respiratory muscles. The exhaled NO value was only significantly increased after the supplementation (26% p < 0.001) in the L-citrulline condition. Pulmonary function, MIP, rate of perceived exertion, and sternocleidomastoid muscle oxygenation were not affected by the L-citrulline supplementation. In the present study, although short-term L-citrulline supplementation increased exhaled NO , no ergogenic aids were found on the examined parameters at rest and after resistive breathing to task failure in older adults.
Databáze: MEDLINE