| Autor: |
Lai JS; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 117609, Singapore., Colega MT; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 117609, Singapore., Godfrey KM; MRC Lifecourse Epidemiology Centre & NIHR Southampton Biomedical Research Centre, University of Southampton & University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK., Tan KH; Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore 229899, Singapore., Yap F; Duke-NUS Medical School, Singapore 169857, Singapore.; Department of Paediatric Endocrinology, KK Women's and Children's Hospital, Singapore 229899, Singapore., Chong YS; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 117609, Singapore.; Department of Obstetrics & Gynaecology and Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore 119228, Singapore., Lee YS; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore 119228, Singapore., Eriksson JG; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 117609, Singapore.; Department of Obstetrics & Gynaecology and Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore 119228, Singapore.; Finland and Folkhälsan Research Center, University of Helsinki, Helsinki 00014, Finland., Chan SY; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 117609, Singapore.; Department of Obstetrics & Gynaecology and Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore 119228, Singapore., Chong MFF; Singapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 117609, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore. |
| Abstrakt: |
Adopting a healthy diet during and after pregnancy is important for women's cardiometabolic health. We related changes in diet quality from pregnancy to 6 years postpregnancy to cardiometabolic markers 8 years postpregnancy. In 652 women from the GUSTO cohort, we assessed dietary intakes at 26-28 weeks' gestation and 6 years postpregnancy using 24 h recall and a food frequency questionnaire, respectively; diet quality was scored using a modified Healthy Eating Index for Singaporean women. Diet quality quartiles were derived; stable, large/small improvement/decline in diet quality as no change, >1 or 1 quartile increase/decrease. Fasting triglyceride (TG), total-, high- and low-density-lipoprotein cholesterol (TC, HDL- and LDL-C), glucose and insulin were measured 8 years postpregnancy; homeostatic model assessment for insulin resistance (HOMA-IR) and TG: HDL-C ratio were derived. Linear regressions examined changes in diet quality quartiles and cardiometabolic markers. Compared to a stable diet quality, a large improvement was associated with lower postpregnancy TG [-0.17 (-0.32, -0.01) mmol/L], TG: HDL-C ratio [-0.21 (-0.35, -0.07) mmol/L], and HOMA-IR [-0.47 (-0.90, -0.03)]; a large decline was associated with higher postpregnancy TC and LDL-C [0.25 (0.02, 0.49); 0.20 (0.004, 0.40) mmol/L]. Improving or preventing a decline in diet quality postpregnancy may improve lipid profile and insulin resistance. |
