Association of Electrical Cardioversion with Brain Perfusion and Cognitive Function in Patients with Atrial Fibrillation.

Autor: Kedžo J; Department of Cardiology, University Hospital of Split, 21000 Split, Croatia., Lovrić Kojundžić S; Department of Diagnostic and Interventional Radiology, University Hospital of Split, 21000 Split, Croatia.; University Department of Health Studies, University of Split, 21000 Split, Croatia.; School of Medicine, University of Split, 21000 Split, Croatia., Marinović Guić M; Department of Diagnostic and Interventional Radiology, University Hospital of Split, 21000 Split, Croatia.; University Department of Health Studies, University of Split, 21000 Split, Croatia.; School of Medicine, University of Split, 21000 Split, Croatia., Tandara L; School of Medicine, University of Split, 21000 Split, Croatia.; Medical Laboratory Diagnostic Division, Medical Biochemistry and Laboratory Medicine Subdivision, University Hospital of Split, 21000 Split, Croatia., Brešković T; Department of Cardiology, University Hospital of Split, 21000 Split, Croatia., Jurišić Z; Department of Cardiology, University Hospital of Split, 21000 Split, Croatia.
Jazyk: angličtina
Zdroj: Life (Basel, Switzerland) [Life (Basel)] 2023 Apr 03; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 03.
DOI: 10.3390/life13040935
Abstrakt: Background: The association of atrial fibrillation (AF) and brain perfusion (BP) has not been well-defined. This study aimed to determine the association of persistent AF with BP and cognition, in comparison to control subjects and with regards to electrical cardioversion (ECV).
Methods: This study compared 25 patients with persistent AF undergoing elective ECV with 16 age/sex-matched controls. We measured regional BP by using the magnetic resonance (MRI) arterial spin labelling technique. Cognitive function was assessed using the Patient-Reported Outcomes Measurement Information System (PROMIS) cognitive function index. Measurements were performed at baseline and 6 weeks after ECV.
Results: There was no significant difference in BP between AF patients and control subjects ( p > 0.05). Following the ECV, there was a significant improvement in BP in 15 patients who maintained sinus rhythm, while there was no significant change in the recurrence group (297 ± 24 before vs. 328 ± 37 after ECV, p = 0.008, and 297 ± 22 before vs. 307 ± 24 after ECV, p = 0.45, respectively). There was no difference in the cognitive assessment between AF patients and control subjects, as well as before and after ECV within the AF group (52.2 ± 9.6 vs. 51.2 ± 6.2, p = 0.71 and 53 ± 10 vs. 54 ± 9, p = 0.46, respectively).
Conclusions: This study did not show difference in BP between persistent AF patients and matched control subjects. Restoration of sinus rhythm was associated with significantly improved BP. There was no association of ECV and changes in cognitive function.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje