| Autor: |
Pérez-Sánchez AP; Hospital Veterinario para Pequeñas Especies de la Facultad de Medicina Veterinaria y Zootecnia-Universidad Autonoma del Estado de México, Toluca 50130, Mexico., Perini-Perera S; Hospital Veterinario para Pequeñas Especies de la Facultad de Medicina Veterinaria y Zootecnia-Universidad Autonoma del Estado de México, Toluca 50130, Mexico.; Hospital Veterinario de Pequeños Animales, Facultad de Veterinaria, Universidad de la República, Montevideo 13000, Uruguay., Del-Angel-Caraza J; Hospital Veterinario para Pequeñas Especies de la Facultad de Medicina Veterinaria y Zootecnia-Universidad Autonoma del Estado de México, Toluca 50130, Mexico., Quijano-Hernández IA; Hospital Veterinario para Pequeñas Especies de la Facultad de Medicina Veterinaria y Zootecnia-Universidad Autonoma del Estado de México, Toluca 50130, Mexico., Recillas-Morales S; Hospital Veterinario para Pequeñas Especies de la Facultad de Medicina Veterinaria y Zootecnia-Universidad Autonoma del Estado de México, Toluca 50130, Mexico. |
| Jazyk: |
angličtina |
| Zdroj: |
Animals : an open access journal from MDPI [Animals (Basel)] 2023 Apr 19; Vol. 13 (8). Date of Electronic Publication: 2023 Apr 19. |
| DOI: |
10.3390/ani13081399 |
| Abstrakt: |
In animals with chronic pathologies, the detection of proteinuria via the proteinuria: creatininuria ratio (UPC) and urinary protein electrophoresis allows for the early diagnosis of chronic kidney disease (CKD). The objective of this work was to identify and determine the magnitude of proteinuria and its electrophoretic pattern characterization in dogs with chronic diseases pathophysiologically related to proteinuria. With the studied patients, five groups were formed. The control group (CG) contained non-proteinuric cases. The cases with proteinuria were classified into four groups according to the concurrent disease: chronic inflammatory diseases (IG), neoplasms (NG), heart diseases (HG), and endocrine diseases (EG). For the statistical analysis, descriptive statistics and non-parametric tests were used. Data from 264 dogs were obtained; in the disease groups, proteinuria was observed in more than 30% as the only finding of kidney disease, evidencing a greater risk factor for proteinuria in the HG group (OR 4.047, CI 1.894-8.644, p < 0.0001). In the HG, NG, and EG groups, a higher frequency of glomerular pattern (GEP) related to glomerular hypertension was observed; in the IG, a higher frequency of mixed pattern (MEP) was observed. These findings are secondary to the hyperfiltration process that affects the glomerulus and the renal tubule. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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