| Autor: |
Dantas GHM; Department of Physical Activity Sciences (DCAF), Laboratory of Exercise and Sport (LABEES); Postgraduate Program in Exercise and Sport Sciences, Institute of Physical Education and Sports, Rio de Janeiro State University, Rio de Janeiro, Brazil., Oliveira ALB; Physical Education College, Federal University of Mato Grosso, Cuiabá, Brazil., Marcos-Pardo PJ; CERNEP, Research Centre, SPORT Research Group (CTS-1024), University of Almería, 04120 Almería, Spain; CERNEP, Research Centre, SPORT Research Group (CTS-1024), University of Almería, 04120 Almería, Spain; Active Aging, Exercise and Health/HEALTHY-AGE Network, Consejo Superior de Deportes (CSD), Ministry of Culture and Sport of Spain, 28040 Madrid, Spain,, Spain., Coutinho VFF; Intensive Care Unit, Hospital San Francisco Providence of God, Rio de Janeiro, Rio de Janeiro, Brazil., Sá Freire FC; Urology Service, Pedro Ernesto University Hospital, Rio de Janeiro, Brazil., Castro JBP; Department of Physical Activity Sciences (DCAF), Laboratory of Exercise and Sport (LABEES); Postgraduate Program in Exercise and Sport Sciences, Institute of Physical Education and Sports, Rio de Janeiro State University, Rio de Janeiro, Brazil., Souza Vale RG; Department of Physical Activity Sciences (DCAF), Laboratory of Exercise and Sport (LABEES); Postgraduate Program in Exercise and Sport Sciences, Institute of Physical Education and Sports, Rio de Janeiro State University; Laboratory of Exercise Physiology, Estácio de SáUniversity, Cabo Frio, Rio de Janeiro, Brazil. |
| Abstrakt: |
McArdle's disease, known as blockage of muscle glycogen metabolism, is characterized by glycogen accumulation of chains in skeletal striated muscles. One of the typical symptoms of the disease is the feeling of intolerance to exercise. Severe muscle cram and contracture, which often cause stiffness, occur due to a lack of muscle energy substrate during the exercise. These factors can lead to muscle damage, myoglobinuria, and, in severe cases, renal failure and rhabdomyolysis. Rhabdomyolysis is a syndrome that presents injury and necrosis of muscle cells leading to the release of intracellular material to the circulatory system. The present study aimed to report rhabdomyolysis in an individual with McArdle's disease after exercise of walking with low intensity. Patient, aged 33 years, was treated in the emergency room of a hospital located in the State of Rio de Janeiro, Brazil. After performing a full lap on the block of home (~500 m in ~4 min 37 s), walking at a moderate speed (~6.5 km/h), the individual felt sick and was rescued, later being hospitalized. The examinations collected presented hematocrit (HCT) compatible with chronic disease anemia and myoglobinuria. The patient was discharged from the intensive care center on the 3 rd day, after a 45% drop in creatine kinase. The patient described in the present study achieved full recovery. Attention to symptoms, early diagnosis, and immediate treatment made it possible to interrupt the development of complications caused by rhabdomyolysis, not allowing progression to acute renal failure. |
