Glomerular Diseases in the Colombian Caribbean: Data from the Colombian Nephropathy Registry (NEFRORED®).

Autor: Aroca-Martínez G; Faculty of Health Sciences, Simón Bolívar University; Department of Nephrology, Clínica de la Costa, Barranquilla, Colombia., González-Torres HJ; Faculty of Health Sciences, Simón Bolívar University, Barranquilla; PhD in Biomedical Sciences, Universidad del Valle, Cali, Colombia., Domínguez-Vargas A; Department of Nephrology, Clínica de la Costa; Division of Health Sciences, Universidad del Norte, Barranquilla, Colombia., García-Tolosa R; Department of Nephrology, Clínica de la Costa, Barranquilla, Colombia., Castillo-Parodi L; Faculty of Health Sciences, Simón Bolívar University; Department of Nephrology, Clínica de la Costa, Barranquilla, Colombia., Conde-Manotas J; Faculty of Health Sciences, Simón Bolívar University; Department of Nephrology, Clínica de la Costa, Barranquilla, Colombia., Navarro-Quiroz E; Faculty of Health Sciences, Simón Bolívar University, Barranquilla, Colombia., Acuña-Freyte A; Faculty of Health Sciences, Simón Bolívar University, Barranquilla, Colombia., Musso CG; Faculty of Health Sciences, Simón Bolívar University, Barranquilla, Colombia; Ageing Biology Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Colombia., Depine SA; Quality Department, Confederation of Dialysis Associations of the Republic of Argentina, Buenos Aires, Argentina., Cadena-Bonfanti A; Faculty of Health Sciences, Simón Bolívar University; Department of Nephrology, Clínica de la Costa, Barranquilla, Colombia.
Jazyk: angličtina
Zdroj: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia [Saudi J Kidney Dis Transpl] 2022 Feb; Vol. 33 (Supplement), pp. S18-S29.
DOI: 10.4103/1319-2442.374379
Abstrakt: Our study aimed to describe the glomerular diseases, both primary glomerular disease (PGD) and secondary glomerular disease (SGD) in the Colombian Caribbean based on the first regional Colombian Nephropathy Registry (NEFRORED®). A descriptive and retrospective study of adult patients with glomerular diseases from the Colombian Caribbean region was made. All diagnoses by renal biopsy with light microscopy and immunofluorescence obtained between January 2008 and June 2018 were recorded. Eight hundred and seventy-one renal biopsies were obtained. The main clinical indication for biopsy was nephritic syndrome (36%). SGD was more frequent than PGD (55% vs. 45%). Within SGD group, lupus nephritis (LN) was the most frequent etiology (83%). Within PGD group, membranous nephropathy (33%) and focal segmental glomerulosclerosis (FSGS) (19%) were the most common glomerular diseases. At a 24-month follow-up, the patients with FSGS and paraproteinemia-mediated glomerular disease had the worst renal survival prognosis. This is the first Colombian Nephropathy Registry in a Caribbean population, demonstrating a high predominance of SGD due to LN.
Databáze: MEDLINE