Impact of X-Ray Exposure From Computed Tomography on Wearable Insulin Delivery Devices.

Autor:	Dong F; The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Johnson P; Imaging Institute, Cleveland Clinic, Cleveland, OH, USA., Fong G; Imaging Institute, Cleveland Clinic, Cleveland, OH, USA., Nguyen A; Insulet Corporation, Acton, MA, USA., Lauand F; Insulet Corporation, Acton, MA, USA., Vienneau T; Insulet Corporation, Acton, MA, USA.
Jazyk:	angličtina
Zdroj:	Journal of diabetes science and technology [J Diabetes Sci Technol] 2024 Nov; Vol. 18 (6), pp. 1387-1391. Date of Electronic Publication: 2023 Apr 26.
DOI:	10.1177/19322968231169722
Abstrakt:	Background: To investigate the impact of radiation exposure from a computed tomography (CT) scanner on the functional integrity of a wearable insulin delivery system. Methods: A total of 160 Omnipods and four personal diabetes managers (PDMs) were evenly divided into four groups: (1) control group (no radiation exposure), (2) typical radiation exposure group, (3) 4× typical radiation exposure group, and (4) scatter radiation group. Pods were attached to an anthropomorphic torso phantom on the abdomen (direct irradiation) or shoulder (scatter radiation) region. A third-generation dual-source CT scanner was used to scan the pods using either a typical exposure (used for routine CT abdominal study of a median size patient) or 4× typical exposure. A manufacturer-recommended 20-step functionality test was performed for all 160 Omnipods. Results: The radiation dose (measured in volume CT Dose index) was 16 mGy for a typical exposure, and 64 mGy for 4× typical exposure. The scatter radiation is less than 0.1 mGy. All Pods passed the functionality test except one pod in the scatter radiation group, which sounded an alarm due to occlusion. The blockage to the fluid was due to a kink in the soft cannula, a mechanical issue not caused by the radiation exposure. Conclusions: This study suggests X-ray exposure levels used in radiological imaging procedures do not negatively impact the functional integrity of Omnipods. This finding may support the potential for the manufacturer to remove the warning that patients should remove the Pod for X-ray imaging procedures, which will have a huge impact on patient care. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Alex Nguyen, Felipe Lauand, and Todd Vienneau are employees of Insulet, Inc.
Databáze:	MEDLINE
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