Kidney biopsy in subsaharan Africa
| Autor: | N'Dah KJ; CHU de Bouaké, service d’anatomie et cytologie pathologiques, Bouaké, Côte d’Ivoire, Tia WM; CHU de Bouaké, service de néphrologie, Bouaké, Côte d’Ivoire, Lagou DA; CHU de Yopougon, service de néphrologie, Abidjan, Côte d’Ivoire, Guei MC; CHU de Yopougon, service de néphrologie, Abidjan, Côte d’Ivoire, Abouna AD; CHU de Cocody, service d’anatomie et cytologie pathologiques, Abidjan, Côte d’Ivoire, Touré I; CHU de Bouaké, service d’anatomie et cytologie pathologiques, Bouaké, Côte d’Ivoire, Oka KH; CHU de Bouaké, service d’anatomie et cytologie pathologiques, Bouaké, Côte d’Ivoire, Kobenan A; CHU de Bouaké, service d’anatomie et cytologie pathologiques, Bouaké, Côte d’Ivoire, Diopo S; CHU de Treichville, service de néphrologie, Abidjan, Côte d’Ivoire, Delma S; CHU Blaise Compaoré, service de néphrologie, Ouagadougou, Burkina Faso, Cherif I; CHU Donka, service de néphrologie, Conakry, Guinée, Amékoudi E; CHU Sylvanus Olympio, service de néphrologie, Lomé, Togo, Ouattara BS; CHU de Cocody, service d’anatomie et cytologie pathologiques, Abidjan, Côte d’Ivoire, Yao KH; CHU de Treichville, service de néphrologie, Abidjan, Côte d’Ivoire, Ackoundou NC; CHU de Yopougon, service de néphrologie, Abidjan, Côte d’Ivoire, Adonis KL; CHU de Yopougon, service de néphropédiatrie, Abidjan, Côte d’Ivoire, Yao GV; CHU de Bouaké, service d’anatomie et cytologie pathologiques, Bouaké, Côte d’Ivoire, Gnionsahié DA; CHU de Bouaké, service de néphrologie, Bouaké, Côte d’Ivoire, Diomandé M; CHU de Cocody, service d’anatomie et cytologie pathologiques, Abidjan, Côte d’Ivoire |
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| Jazyk: | francouzština |
| Zdroj: | Nephrologie & therapeutique [Nephrol Ther] 2023 Apr 26; Vol. 19 (2), pp. 99-108. |
| DOI: | 10.1684/ndt.2023.9 |
| Abstrakt: | Materials and Methods: We carried out a retrospective and descriptive study on biopsies examined between January 2015 and December 2019, in the pathological departments of University Teaching Hospital of Bouaké and Cocody-Abidjan. The KB came from four countries (Côte d'Ivoire, Togo, Guinea-Conakry and Burkina Faso). Optical microscopy and/or direct immunofluorescence techniques were used. All biopsy samples including epidemiological, clinical and pathological data and an optical microscopy and/or direct immunofluorescence study were included. The parameters studied were indications for KB, epidemiological profile, clinic, proteinuria and pathological aspects. Results: Over the study period, we collected 179 KB, i.e. 35.8 KB/year. The mean age of the patients was 32.9 ±13.8 years (range 11-70 years). The sex ratio (M/F) was 1.03. Pure nephrotic syndrome was the main indication (64.2 %, n = 115) for KB, followed by impure nephrotic syndrome (11.7 %, n = 21), acute renal failure (ARF) (7.8 %, n = 14) and rapidly progressive glomerulonephritis (RPGN) (7.8 %, n = 14). Glomerulonephritis (GN) occurred in 86 % (n = 158), vascular nephropathy in 11.7 % (n = 21) and tubulointerstitial nephritis in 2.2 % (n = 4). The nephropathies were preferentially focal segmental glomerulosclerosis (34.6 %, n = 62), nephroangiosclerosis (10.6 %, n = 19), membranous GN (10 %, n = 18), post-infectious GN (8.9 %, n = 16) and lupus GN (7.3 %, n = 13). Conclusion: The KB is an essential step in the diagnosis of nephropathies. Focal segmental glomerulosclerosis is frequent in our study. The establishment of a Kidney registry would allow better knowledge of renal pathologies in sub-Saharan Africa. |
| Databáze: | MEDLINE |
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