Recent synthetic approaches towards thienothiophenes: a potential template for biologically active compounds.

Autor: Rafiq A; Department of Chemistry, Government College University, Faisalabad, 38000, Pakistan., Aslam S; Department of Chemistry, Government College Women University, Faisalabad, 38000, Pakistan., Ahmad M; Department of Chemistry, Government College University, Faisalabad, 38000, Pakistan. Matloob.Ahmad@gcuf.edu.pk., Nazir MS; Department of Chemistry, Government College University, Faisalabad, 38000, Pakistan., Farooq A; Department of Chemistry, Government College University, Faisalabad, 38000, Pakistan., Sultan S; Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam 42300, Shah Alam, Selangor Darul Ehsan, Malaysia.; Atta-Ur-Rahman Institute for Natural Products Discovery (AuRIns), Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam 42300, Shah Alam, Selangor Darul Ehsan, Malaysia.
Jazyk: angličtina
Zdroj: Molecular diversity [Mol Divers] 2024 Jun; Vol. 28 (3), pp. 1793-1821. Date of Electronic Publication: 2023 Apr 24.
DOI: 10.1007/s11030-023-10647-1
Abstrakt: Heterocyclic compounds are attractive candidates because of their vast applications in natural and physical sciences. Thienothiophene (TT) is an annulated ring of two thiophene rings with a stable and electron-rich structure. Thienothiophenes (TTs) fully represent the planar system, which can drastically alter or improve the fundamental properties of organic, π-conjugated materials when included into a molecular architecture. These molecules possessed many applications including, pharmaceutical as well as optoelectronic properties. Different isomeric forms of thienothiophene showed various applications such as antiviral, antitumor, antiglaucoma, antimicrobial, and as semiconductors, solar cells, organic field effect transistors, electroluminiscents etc. A number of methodologies were adopted to synthesize thienothiophene derivatives. In this review, we have addressed different synthetic strategies of various isomeric forms of thienothiophene that have been reported during last seven years, i.e., 2016-2022.
(© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Databáze: MEDLINE
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