Coinfection of COVID-19 and Tuberculosis in Uganda.

Autor: Nuwagira E; Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.; Tuberculosis Treatment Unit, Mbarara Regional Referral Hospital, Mbarara, Uganda., Mpagama SG; Infectious Diseases Unit, Kibong'oto Infectious Disease Hospital, Kilimanjaro, Tanzania., Katusiime A; Tuberculosis Treatment Unit, Mbarara Regional Referral Hospital, Mbarara, Uganda., Natamba B; Tuberculosis Treatment Unit, Mbarara Regional Referral Hospital, Mbarara, Uganda., Baluku JB; Division of Pulmonology, Kiruddu National Referral Hospital, Kampala, Uganda., Lai PS; Division of Pulmonology, Massachusetts General Hospital, Boston, Massachusetts.
Jazyk: angličtina
Zdroj: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2023 Apr 24; Vol. 108 (6), pp. 1240-1243. Date of Electronic Publication: 2023 Apr 24 (Print Publication: 2023).
DOI: 10.4269/ajtmh.22-0738
Abstrakt: The clinical features and outcomes of tuberculosis (TB) and COVID-19 coinfection are not well established. This short report describes 11 people with TB/COVID-19 coinfection in Uganda. The mean age was 46.9 ± 14.5 years; eight (72.7%) were male and two (18.2%) were coinfected with HIV. All patients presented with cough whose median duration was 71.1 (interquartile range, 33.1, 109) days. Eight (72.7%) had mild COVID-19 whereas two (18.2%) died, including one with advanced HIV disease. All patients were treated with first-line anti-TB drugs and adjunct therapy for COVID-19 using national treatment guidelines. This report presents the possibility of the coexistence of the two diseases and calls for more vigilance, screening, and collective prevention measures for both COVID-19 and TB.
Databáze: MEDLINE