Celiac disease seroprevalence in patients with infertility. A case-control study.

Autor:	Remes-Troche JM; Laboratory of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana., Sánchez-Vargas LA; Laboratory of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana., Ríos-Gálvez S; Laboratory of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana., Cano-Contreras AD; Laboratory of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana., Amerena-Abreu J; Fertilización in Vitro de Veracruz, Centro FIVER. Veracruz, Mexico., Cruz-Patiño E; Laboratory of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana., Meixueiro-Daza A; Laboratory of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana., Vivanco-Cid H; Laboratory of Digestive Physiology and Gastrointestinal Motility, Institute of Medical-Biological Research, Universidad Veracruzana.
Jazyk:	angličtina
Zdroj:	Gaceta medica de Mexico [Gac Med Mex] 2023; Vol. 159 (2), pp. 142-146.
DOI:	10.24875/GMM.M23000762
Abstrakt:	Background: Although most patients with celiac disease (CD) have digestive manifestations, in some of them they may be of extraintestinal (atypical) nature, such as chronic anemia, ataxia, and fertility disorders. Objective: To determine the prevalence of CD-related antibodies in Mexican women with fertility disorders. Material and Methods: Case-control study of women who attended evaluation for fertility disorders in a specialized center. h-tTG-IgA, gliadin IgA II and gliadin IgG II were quantified; titers > 30 IU were considered positive. Results: One-hundred and seventy-one cases and 171 controls were included; 137 patients (80.1%) had infertility, and 34 (19.9%), sterility. Eight patients (4.6%, 95% CI = 2.3-8.9) had at least one positive marker for CD in comparison with one woman in the control group (0.5%, 95% CI = 0.01-3, p = 0.04, odds ratio = 8.3). Six of the eight patients had unexplained infertility. Conclusions: Up to 4.6% of women with infertility had at least one positive marker for CD. As in other parts of the world, screening for CD could be recommended in women with infertility, especially in those with unexplained infertility. (Copyright: © 2023 Permanyer.)
Databáze:	MEDLINE
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