| Autor: |
Jafarpour Mahalleh A; Student Research Committee, Tabriz University of Medical Sciences, Tabriz 13147-15311, Iran., Mesgarzadeh AH; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 13147-15311, Iran., Jarolmasjed S; Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz 51666-16471, Iran., Soltani Somee A; Department of Physiotherapy, Faculty of Rehabilitation Sciences, Tabriz University of Medical Sciences, Tabriz 13147-15311, Iran., Khordadmehr M; Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz 51666-16471, Iran., Rezaei Y; Department of Dental Biomaterials, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 13147-15311, Iran., Maleki Dizaj S; Department of Dental Biomaterials, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz 13147-15311, Iran.; Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 13147-15311, Iran., Shahi S; Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 13147-15311, Iran. |
| Abstrakt: |
The aim of this study was to assess the multi-phasic use of extracorporeal shock wave therapy (ESWT) as an adjuvant treatment to accelerate the osseointegration of titanium dental implants. Initially, twelve titanium mini-screws were inserted in femur bones of six New Zealand rabbits in three groups; the one-time treated group, the three-time treated group, and the control group (without ESWT). Then, 1800 focused shockwaves with an energy flux density of 0.3 mJ/mm 2 in every phase were used. Fourteen days after the last phase of ESWT, the animals were sacrificed to assess the osseointegration of screws via micro-computed tomography scan (micro-CT scan), biomechanical pull-out test, and histopathological analysis. Pull-out and histopathology analysis showed that the ESWT significantly increased bone regeneration and osseointegration around the implants compared to the control group ( p < 0.05). Moreover, the pull-out test confirmed that the three-time treated screws needed more force to pull the bone out compared to the other two groups ( p < 0.05). The mean bone volume fraction between the control group, the one-time treated group, and the three-time treatment group were not statistically significant ( p > 0.05) according to the micro-CT scan results. Based on our results, ESWT can be suggested as a non-invasive and cost-effective adjuvant for osseointegration of dental implants. However, more in vivo studies and clinical trials are needed for validation of this finding. |
