Chest Pain in Acute Myocardial Infarction and Its Association With the Culprit Artery and Fibrotic Segment Identified by Cardiac Magnetic Resonance.

Autor: Leite WF; Department of Hypertensive Heart Disease, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Dos Santos Povoa RM; Department of Hypertensive Heart Disease, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Caixeta AM; Department of Hemodynamics, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Amodeo C; Department of Hypertensive Heart Disease, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Szarf G; Department of Magnetic Resonance, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Bombig MTN; Department of Hypertensive Heart Disease, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Izar MCO; Department of Lipids, Atherosclerosis and Vascular Biology, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Gioia LN; Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Ribeiro WN; Department of Coronary Artery Disease, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil., Fonseca FAH; Department of Lipids, Atherosclerosis and Vascular Biology, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, SP, Brazil.
Jazyk: angličtina
Zdroj: Cardiology research [Cardiol Res] 2023 Apr; Vol. 14 (2), pp. 97-105. Date of Electronic Publication: 2023 Apr 08.
DOI: 10.14740/cr1468
Abstrakt: Background: It is still very controversial whether the characteristics of pain in the acute myocardial infarction could be related to the culprit coronary artery. There are no data about associations of pain with the ST-segment elevation myocardial infarction (STEMI) and left ventricular (LV) fibrotic segments.
Methods: Data from 328 participants who had STEMI and were included in the B and T Types of Lymphocytes Evaluation in Acute Myocardial Infarction (BATTLE-AMI) study were analyzed. The culprit artery was identified by coronary angiography and the injured myocardial segments by cardiac magnetic resonance. The statistical significance was established by P value < 0.05.
Results: A total of 223 patients (68%) were selected. Association was not observed between chest pain and the culprit artery (P = 0.237), as well as between pain irradiation and the culprit artery (P = 0.473). No significant difference was observed in the pain localization in relation to the segments in the short axis basal, mid, apical, and long axis, except for the mid inferior segment. The data were not considered clinically relevant because this association was observed in only one of 17 segments after multiple comparisons.
Conclusions: In patients with STEMI, no associations were observed between the location or irradiation of acute chest pain and/or adjacent areas and the culprit artery, or between pain and segmental myocardial fibrosis in the LV.
Competing Interests: The authors declare that they have no conflict of interests.
(Copyright 2023, Leite et al.)
Databáze: MEDLINE