Relationship between lower urinary tract symptoms and frailty.

Autor: Ozaki Y; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Hatakeyama S; Department of Advanced Blood Purification Therapy, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Imai A; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Songee J; Department of Innovation Center for Health Promotion, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Soma O; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Ozaki K; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Fujita N; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Okamoto T; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Iwamura H; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Yamamoto H; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Yoneyama T; Department of Advanced Transplant and Regenerative Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Hashimoto Y; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Ohyama C; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.; Department of Advanced Blood Purification Therapy, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.; Department of Advanced Transplant and Regenerative Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Jazyk: angličtina
Zdroj: International journal of urology : official journal of the Japanese Urological Association [Int J Urol] 2023 Jul; Vol. 30 (7), pp. 606-613. Date of Electronic Publication: 2023 Apr 23.
DOI: 10.1111/iju.15187
Abstrakt: Objective: To elucidate the relationship between frailty and lower urinary tract symptoms (LUTS).
Methods: We longitudinally evaluated the temporal changes and the relationships between frailty and LUTS in 247 community-dwelling adults (45 years or older) at baseline and at a 5-year follow-up. We used the Fried phenotype (phenotype-based frailty), 5-item modified frailty index (5i-mFI; comorbidity-based frailty), and frailty discriminant score (comprehensive frailty assessment) to evaluate frailty. LUTS were evaluated using the international prostate symptom score (IPSS) and overactive bladder symptom score (OABSS).
Results: We analyzed 247 participants with a median age of 60 years. The median IPSS and OABSS were significantly increased over the 5 years. The proportion of frail individuals did not increase significantly over the 5 years. Of the three frailty assessment tools, the 5i-mFI score significantly increased between 2014 and 2019. Multiple linear regression analyses showed that the 5i-mFI score was significantly associated with the severity of LUTS in 2014 to 5i-mFI in 2019 but not with 5i-mFI in 2014 to the severity of LUTS in 2019.
Conclusion: The effect of LUTS on frailty might be greater than the effect of frailty on LUTS. Further large-scale studies are needed to elucidate the relationship between LUTS and frailty.
(© 2023 The Japanese Urological Association.)
Databáze: MEDLINE
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