A cross-sectional analysis of psychosocial and structural barriers and facilitators associated with PrEP use among a sample of transgender women in Chicago, IL.

Autor: Kuhns LM; Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA. lkuhns@luriechildrens.org.; Division of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA. lkuhns@luriechildrens.org., Perloff J; Chicago House and Social Service Agency, Chicago, IL, USA., Johnson AK; Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.; Division of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Paul JL; Chicago House and Social Service Agency, Chicago, IL, USA., Pleasant K; Chicago House and Social Service Agency, Chicago, IL, USA., Evans K; Chicago House and Social Service Agency, Chicago, IL, USA., Denson DJ; Centers for Disease Control and Prevention, Atlanta, GA, USA., Gelaude DJ; Centers for Disease Control and Prevention, Atlanta, GA, USA., Bessler PA; Centers for Disease Control and Prevention, Atlanta, GA, USA., Diskin R; Division of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Cervantes M; Division of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Garofalo R; Department of Pediatrics, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.; Division of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Hotton AL; Department of Medicine, University of Chicago, Chicago, IL, USA.
Jazyk: angličtina
Zdroj: AIDS research and therapy [AIDS Res Ther] 2023 Apr 21; Vol. 20 (1), pp. 24. Date of Electronic Publication: 2023 Apr 21.
DOI: 10.1186/s12981-023-00516-0
Abstrakt: Background: Expanding pre-exposure prophylaxis (PrEP) among transgender women in the United States is an important strategy to meet national HIV prevention goals, however self-reported use of PrEP is low in this group.
Methods: This study reports the findings of a cross-sectional analysis of the relationship of barriers as well as facilitators to recent PrEP use among transgender women enrolled in an evaluation of the TransLife Care project (Chicago, Illinois), a structural intervention designed to meet basic needs. We computed multivariable prevalence ratios for barriers, facilitators and recent PrEP use, controlling for demographics.
Results: Findings suggest that psychosocial and structural barriers, including moderate/high alcohol use, stimulant use, and history of incarceration were all positively associated with recent PrEP use among urban transgender women. In addition, a psychosocial facilitator, gender affirmation, was positively associated with recent PrEP use, while, while collective self-esteem, a was negatively associated with it. Finally, common indications for PrEP have high sensitivity, but low specificity and predictive value for identifying those on PrEP.
Conclusion: We conclude that despite a large gap in PrEP use among those with indications, individuals experiencing psychosocial and structural barriers are more likely to use PrEP, and facilitators, such as psychological sense of affirmed gender may support its use.
Trial Registration: N/A.
(© 2023. The Author(s).)
Databáze: MEDLINE
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