Complex Lemierre syndrome with multisystemic abscesses.

Autor: Bourgeaud J; Internal Medicine, CHUV, Lausanne, Switzerland johan.bourgeaud@chuv.ch., Delabays B; Internal Medicine, CHUV, Lausanne, Switzerland., Van den Bogaart L; Infectious Diseases, CHUV, Lausanne, Switzerland., Ratano D; Adults Intensive Care, CHUV, Lausanne, Switzerland.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2023 Apr 21; Vol. 16 (4). Date of Electronic Publication: 2023 Apr 21.
DOI: 10.1136/bcr-2023-254638
Abstrakt: We present here the challenging case of severe Lemierre syndrome in a healthy woman in her late twenties, whose clinical presentation was characterised by lung abscesses and disseminated systemic abscesses in the brain, the abdomen and the soft-tissues, as a likely consequence of a patent foramen ovale. Blood cultures were positive for Fusobacterium necrophorum and a right lingual vein thrombosis was detected at a late stage when the patient developed a septic shock. Initial antimicrobial therapy with metronidazole and ceftriaxone was modified to meropenem due to progressive worsening. The patient underwent laparoscopy and neurosurgical drainage of a cerebral abscess. She spent many days in the intensive care unit and recovered fully after 6 weeks on meropenem therapy. Although considered rare, the incidence of Lemierre syndrome, a potentially life-threatening condition, is increasing. The clinician should promptly recognise and treat it while being aware of its potential atypical presentations.
Competing Interests: Competing interests: None declared.
(© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE