Human microbiome transfer in the built environment differs based on occupants, objects, and buildings.

Autor: Hoisington AJ; Veterans Health Administration, Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), VISN 19, Aurora, CO, 80045, USA. andrew.hoisington@va.gov.; Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. andrew.hoisington@va.gov.; Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Aurora, CO, 80045, USA. andrew.hoisington@va.gov.; Department of Systems Engineering and Management, US Air Force Institute of Technology, Wright-Patterson Air Force Base, OH, 45433, USA. andrew.hoisington@va.gov., Stamper CE; Veterans Health Administration, Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), VISN 19, Aurora, CO, 80045, USA.; Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Aurora, CO, 80045, USA., Bates KL; Department of Biology, US Air Force Academy, USAF Academy, CO, 80840, USA., Stanislawski MA; Department of Biomedical Informatics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Eastern Colorado Health Care System, Veterans Affairs, Denver, CO, 80220, USA., Flux MC; Department of Psychology and Center for Neuroscience, University of Colorado Boulder, Boulder, CO, 80309, USA., Postolache TT; Veterans Health Administration, Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), VISN 19, Aurora, CO, 80045, USA.; Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Aurora, CO, 80045, USA.; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.; Veterans Health Administration, Mental Illness Research Education and Clinical Center (MIRECC), Baltimore VA Annex, VISN 5, Baltimore, MD, 21201, USA., Lowry CA; Veterans Health Administration, Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), VISN 19, Aurora, CO, 80045, USA.; Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Aurora, CO, 80045, USA.; Department of Integrative Physiology and Center for Neuroscience, University of Colorado Boulder, Boulder, CO, 80309, USA.; Center for Microbial Exploration, University of Colorado Boulder, Boulder, CO, 80309, USA., Brenner LA; Veterans Health Administration, Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), VISN 19, Aurora, CO, 80045, USA.; Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Aurora, CO, 80045, USA.; Departments of Psychiatry and Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Apr 20; Vol. 13 (1), pp. 6446. Date of Electronic Publication: 2023 Apr 20.
DOI: 10.1038/s41598-023-33719-6
Abstrakt: Compared to microbiomes on other skin sites, the bacterial microbiome of the human hand has been found to have greater variability across time. To increase understanding regarding the longitudinal transfer of the hand microbiome to objects in the built environment, and vice versa, 22 participants provided skin microbiome samples from their dominant hands, as well as from frequently and infrequently touched objects in their office environments. Additional longitudinal samples from home environments were obtained from a subset of 11 participants. We observed stability of the microbiomes of both the hand and built environments within the office and home settings; however, differences in the microbial communities were detected across the two built environments. Occupants' frequency of touching an object correlated to that object having a higher relative abundance of human microbes, yet the percent of shared microbes was variable by participants. Finally, objects that were horizontal surfaces in the built environment had higher microbial diversity as compared to objects and the occupants' hands. This study adds to the existing knowledge of microbiomes of the built environment, enables more detailed studies of indoor microbial transfer, and contributes to future models and building interventions to reduce negative outcomes and improve health and well-being.
(© 2023. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)
Databáze: MEDLINE
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