Distinct microtubule networks mediate neuronal migration and polarization.

Autor: Njoku IP; Michigan Neuroscience Institute (MNI), University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA., Kwan KY; Michigan Neuroscience Institute (MNI), University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: kykwan@umich.edu.
Jazyk: angličtina
Zdroj: Neuron [Neuron] 2023 Apr 19; Vol. 111 (8), pp. 1168-1170.
DOI: 10.1016/j.neuron.2023.03.026
Abstrakt: During cortical development, microtubules simultaneously mediate neuronal migration up toward cortical plate and axon extension down toward white matter. Using new molecular tools to manipulate microtubule nucleation and dynamics, in this issue of Neuron, Vinopal et al. 1 identify the distinct microtubule networks underpinning these processes.
Competing Interests: Declaration of interests The authors declare no competing interests.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE