| Autor: |
Pérez-Camargo DA; Department of Nutrition. Instituto Nacional de Cancerología., Allende-Pérez SR; Department of Palliative Care. Instituto Nacional de Cancerología., Rivera-Franco MM; Department of Hematology and Oncology. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán., Urbalejo-Ceniceros VI; Department of Hematology. Instituto Nacional de Cancerología., Sevilla-González ML; Escuela Superior de Medicina. Instituto Politécnico Nacional., Arzate-Mireles CE; Department of Palliative Care. Instituto Nacional de Cancerología., Copca-Mendoza ET; Department of Nutrition. Instituto Nacional de Cancerología. |
| Jazyk: |
angličtina |
| Zdroj: |
Nutricion hospitalaria [Nutr Hosp] 2023 Jun 21; Vol. 40 (3), pp. 626-632. |
| DOI: |
10.20960/nh.04446 |
| Abstrakt: |
Introduction: Introduction: current data regarding the decision on rehydration of patients with terminal-stage cancer remain controversial. Objective: the present study was to evaluate the effect of intravenous hydration and supplementary vitamins and trace elements on clinical symptoms and biochemical parameters in palliative cancer patients. Methods: a randomized clinical trial including 72 palliative cancer patients aged 18 years and older was performed at the National Cancer Institute in Mexico. Patients were divided into two groups: intervention and control, both receiving intravenous saline solution weekly for 4 weeks, but the former was also supplemented with vitamins and trace elements. Symptoms were assessed at baseline and 4 weeks after with the Edmonton Symptom Assessment Scale. Same measurements applied to biochemical parameters. Results: the mean age of the patients was 58.75 years. The most frequent cancer diagnoses were gastrointestinal (32 %). In the between-groups analysis significant improvements were found for the intervention group in anorexia (p = 0.024), pain (p = 0.030), chloride (p = 0.043), phosphorus (p = 0.001), potassium (p = 0.006), and total proteins (< 0.0001). Conclusion: we highlight the improvement in the control of most symptoms and some biochemical parameters in the intervention group receiving vitamins and oligoelements along with intravenous hydration. Further studies are needed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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