Protective effects and mechanism of Paecilomyces cicadae TJJ1213 intracellular polysaccharide against H 2 O 2 -induced PC12 cells damage.
Autor: | Tian J; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China.; College of Tea and Food Science Technology, Jiangsu Vocational College of Agriculture and Forestry, Jurong, China., Xu Q; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China., Wang X; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China., Zhang X; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China., Chen X; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China., Rui X; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China., Zhang Q; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China., Dong M; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China., Li W; College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China. |
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Jazyk: | angličtina |
Zdroj: | Chemical biology & drug design [Chem Biol Drug Des] 2023 Sep; Vol. 102 (3), pp. 471-485. Date of Electronic Publication: 2023 Apr 18. |
DOI: | 10.1111/cbdd.14253 |
Abstrakt: | Oxidative stress is a key process in the development of neurodegenerative diseases. More attention is needed to screen natural antioxidants and explore pharmacological mechanisms. Natural product polysaccharides with no toxic side effects have powerful antioxidant activity. Two purified intracellular polysaccharide fractions (IPS1 and IPS2) from Paecilomyces cicadae TJJ1213 was isolated. Then, a model of H (© 2023 John Wiley & Sons Ltd.) |
Databáze: | MEDLINE |
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