Probable Transmission of SARS-CoV-2 from African Lion to Zoo Employees, Indiana, USA, 2021.

Autor: Siegrist AA, Richardson KL, Ghai RR, Pope B, Yeadon J, Culp B, Behravesh CB, Liu L, Brown JA, Boyer LV
Jazyk: angličtina
Zdroj: Emerging infectious diseases [Emerg Infect Dis] 2023 Jun; Vol. 29 (6), pp. 1102-1108. Date of Electronic Publication: 2023 Apr 17.
DOI: 10.3201/eid2906.230150
Abstrakt: We describe animal-to-human transmission of SARS-CoV-2 in a zoo setting in Indiana, USA. A vaccinated African lion with physical limitations requiring hand feeding tested positive for SARS-CoV-2 after onset of respiratory signs. Zoo employees were screened, monitored prospectively for onset of symptoms, then rescreened as indicated; results were confirmed by using reverse transcription PCR and whole-genome virus sequencing when possible. Traceback investigation narrowed the source of infection to 1 of 6 persons. Three exposed employees subsequently had onset of symptoms, 2 with viral genomes identical to the lion's. Forward contact tracing investigation confirmed probable lion-to-human transmission. Close contact with large cats is a risk factor for bidirectional zoonotic SARS-CoV-2 transmission that should be considered when occupational health and biosecurity practices at zoos are designed and implemented. SARS-CoV-2 rapid testing and detection methods for big cats and other susceptible animals should be developed and validated to enable timely implementation of One Health investigations.
Databáze: MEDLINE