| Autor: |
Takahata T; Dept. of Medical Oncology, Hirosaki University Graduate School of Medicine., Sato A, Terui K, Nakagawa J, Hyodo R, Awatsu A, Abo E, Hasui K, Chen Y, Saito K, Sasaki K |
| Jazyk: |
japonština |
| Zdroj: |
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2023 Apr; Vol. 50 (4), pp. 467-471. |
| Abstrakt: |
We analyzed 4 cases who experienced extravasation of anthracyclines and had dexrazoxane therapy in our hospital. Concerned drugs were 2 adriamycin and 2 amrubicin cases and all cases received steroid ointment therapy, and no cases showed severe condition such as skin ulcer. As dexrazoxane is known to enhance bone marrow suppression of anti-cancer drugs, the nadir of neutropenia and thrombocytopenia was observed from day 10 to 17 in our cases. We made a domestic manual and have used in various professionals. Dexrazoxane would contribute to the reduction of skin damage due to extravasation if we could manage bone marrow suppression successfully. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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